摘要
目的分析43例胃肠道间质瘤(GIST)临床病理特点,结合文献进行讨论。方法回顾性分析重庆市万州区第一人民医院收治的43例经病理诊断证实的GIST患者临床病理及影像学资料。结果43例GIST患者中,发生于胃26例(60.46%)、肠17例(39.54%),直径小于5cm者27例(62.79%),肿瘤边界完整、清楚者38例(88.37%);肿瘤向周围组织发生浸润的有5例(11.63%)、血管推移3例(5.66%);CD117阳性率93.02%(40/43),CD34阳性率81.39%(35/43),DOG1阳性率90.69%(39/43)。结论 GIST临床表现无特异性,MSCT有一定的影像特征性,光镜下与平滑肌瘤、神经鞘瘤及纤维瘤不易鉴别,DOG1、CD117、CD34高表达是确诊的重要依据。
Objective To analyzed 43 cases gastrointestinal stromal tumor （GIST） pathological characteristics, combination with literature were discussed. Methods A retrospective analysis of 43 patients in the first people＇s Hospital of Wenzhou District with pathologically and radiologically confirmed gastrointestinal stromal tumor patient diagnosis, examination results. Results 43 cases of gastrointestinal stromal tumor patients, 26 cases oceured in stomach（60.46 % ）, 17 cases （39.54 % ） in intestines, intestinal diameter were 5 cm in 27 cases （62. 79 %）, the tumor boundary was integrity, clear in 38 cases （88. 37% ） ;the tumor transfer to the surrounding tissue in 5 cases （11.63%） ,3 cases of vascular passage （5.66%） ;the positive rate of CDll7 was 93.2% （40/43） ,the positive rate of CD34 was 81.40% （35/43） ,the positive rate of DOG1 was 90.69% （39/43）. Conclusion The clinical manifesta- tion of gastrointestinal stromal tumors are not specific, MSCT images with certain characteristics, and leiomyoma under light micro- scope,schwannoma and Iibroma can not be identified, the high expression of DOG1, CD117, CD34 is an important basis for diagnosis.
出处
《重庆医学》
CAS
北大核心
2015年第21期2901-2903,共3页
Chongqing medicine
基金
重庆市自然科学基金资助项目(CSTC2013jcyjA10003)
关键词
免疫组织化学
胃肠道间质瘤
临床表现
影像学检查
病理诊断
immunohistochemistry
gastrointestinal stromal tumor
clinical manifestation
ultrasonography
pathologic diagnosis
