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白光内镜下胃黏膜形态判断幽门螺杆菌感染的价值 被引量:2

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摘要 目的探讨白光内镜下胃黏膜形态判断幽门螺杆菌(H.pylori,Hp)感染的价值。方法连续纳入2021年5月至2022年2月于广西壮族自治区柳州市妇幼保健院行胃镜检查的受试者439例,观察胃黏膜形态并取黏膜活检行病理及免疫组化检测Hp,根据胃黏膜形态判断Hp感染情况并与病理检查比较,分析镜下判断Hp的准确性。结果Hp阳性者胃黏膜(regular arrangement of collecting venules,RAC)阴性、黏膜肿胀、萎缩、肠化生、白色浑浊黏液、皱襞肿大蛇形、弥漫性发红、点状发红、消化性溃疡发生率显著高于Hp阴性者(P<0.05);Hp阴性者胃黏膜RAC阳性、脊状发红形态的发生率显著高于Hp阳性者(P<0.05);增生性息肉、胃底腺息肉、隆起糜烂、凹陷性糜烂、陈旧性出血斑的发生率Hp阳性者与阴性者胃黏膜差异无显著性(P>0.05)。RAC阴性的受试者工作特征(receiver operator characteristic,ROC)曲线下面积(area under curve,AUC)、符合率、灵敏度、阳性预测值、阴性预测值均较高(0.832,92.71%,99.71%,91.76%,98.41%),仅特异度稍低(66.67%)。结论白光内镜下根据胃黏膜形态判断Hp具有较高的应用价值,值得在临床应用。
出处 《中国临床医生杂志》 2023年第2期186-189,共4页 Chinese Journal For Clinicians
基金 广西壮族自治区卫生健康委员会自筹经费科研课题(Z20210190)。
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