摘要
目的 分析核磁共振成像(MRI)诊断脑胶质瘤的价值及其预后影响因素。方法 选取2018年8月至2019年8月我院收治确诊为脑胶质瘤病(gliomatosis cerebri,GC)患者120例,均完成MRI检查,分析MRI影像学特点及诊断价值,并总结其预后影响因素。结果 120例GC患者中9类不同瘤质表现出各异的MRI特征;单因素分析显示年龄<60岁、完全切除病灶、术后进行化疗、肿瘤分级Ⅰ-Ⅱ级、肿瘤直径<5cm、术前卡氏预后评分(KPS)≥70分患者生存率较高(P<0.05);多因素分析显示年龄、切除病灶方式、术后化疗、肿瘤分级及肿瘤直径为脑胶质瘤患者预后的独立影响因素(P<0.05)。结论 脑胶质瘤类型及强化程度、囊变形态与肿瘤类型之间存在一定联系,且年龄、切除病灶方式、术后化疗、肿瘤分级及肿瘤直径为脑胶质瘤患者预后的独立影响因素,需根据以上影响因素给予相对应处理措施以改善脑胶质瘤患者预后。
Objective To analyze the value of magnetic resonance imaging(MRI) in the diagnosis of glioma and the influencing factors of prognosis of glioma. Methods 120 patients diagnosed as glioma in the hospital were selected between August 2018 and August 2019, and they all completed MRI examination. The imaging characteristics and diagnostic value of MRI were analyzed and the influencing factors of prognosis were summarized. Results Among the 120 patients with GC, 9 types of tumors showed different MRI characteristics. Univariate analysis showed that the survival rate was higher among patients with age<60 years old, complete resection of lesions, chemotherapy after surgery, tumor gradeⅠ-Ⅱ, tumor diameter<5 cm and preoperative Karnofsky prognosis score(KPS) ≥ 70 points(P<0.05). Multivariate analysis showed that age, lesion resection method, postoperative chemotherapy, tumor grade and tumor diameter were the independent influencing factors for prognosis of patients with glioma(P<0.05). Conclusion There is a certain relationship between the type and enhancement degree of glioma, cystic morphology and type of tumor. In addition, age, lesion resection method, postoperative chemotherapy, tumor grade and tumor diameter are independent factors affecting the prognosis of patients with glioma. It is necessary to take corresponding treatment measures according to the above influencing factors so as to improve the prognosis of patients with glioma.
作者
于虹
王娜
徐苗苗
王嘉奇
YU Hong;WANG Na;XU Miao-miao;WANG Jia-qi(Department of Radiology,Shanghai Proton and Heavy Ion Hospital,Shanghai 201315,China;Shanghai Key Laboratory of Radiation Oncology,Shanghai 201315,China;Shanghai Proton Heavy Ion Radiotherapy Engineering Technology Research Center,Shanghai 201315,China;Department of Radiology,Beijing Sanfine Hospital Co.,Ltd.,Beijing 100027,China;Department of Radiology,The First Hospital of China Medical University,Shenyang 110000,Liaoning Province,China)
出处
《中国CT和MRI杂志》
2023年第1期12-14,共3页
Chinese Journal of CT and MRI
关键词
脑胶质瘤
核磁共振成像
诊断
预后
Glioma
Magnetic Resonance Imaging
Diagnosis
Prognosis
