摘要
乳酸菌细菌素作为一种天然抑菌物质,是化学防腐剂和抗生素的理想替代品。本文从细胞通讯的角度阐述乳酸菌合成细菌素的不同诱导信号来源及其诱导机制,细菌素的合成机制,共培养过程中的多细胞交流以及在复杂环境下的群体感应(QS)信号网络,系统地介绍乳酸菌产细菌素的通讯机制研究进展,为促进细菌素的研究和应用提供参考。
The natural antibacterial substance of bacteriocin produced by lactic acid bacteria is an ideal substitute for chemical preservatives and antibiotics.Cell communication triggers various life activities via signal transmission.In this paper,the cell communication mechanism for producing bacteriocin was described from the aspects including the sources of different inducing signals,the induction mechanism of different signals,the mechanism of bacteriocin synthesis,the multi-cell communication in co-cultivation,and the signal network of quorum sensing(QS)in complex environment.And the research progress on the cell communication mechanism of LAB was systemically introduced.These will provide important reference for promoting the research and application of LAB bacteriocins.
作者
孔令誉
夏超然
沈淇元
曾小群
郭宇星
吴振
潘道东
Kong Lingyu;Xia Chaoran;Shen Qiyuan;Zeng Xiaoqun;Guo Yuxing;Wu Zhen;Pan Daodong(Ningbo University,State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products(Province-Ministry Co-construct),Key Laboratory of Animal Protein Food Processing Technology of Zhejiang Province,College of Food and Pharmaceutical Sciences,Ningbo 315800;Zhejiang 2College of Food Science and Pharmaceutical Engineering,Nanjing Normal University,Nanjing 210097)
出处
《中国食品学报》
EI
CAS
CSCD
北大核心
2022年第12期360-372,共13页
Journal of Chinese Institute Of Food Science and Technology
基金
国家重点研发计划项目(2022YFD2100603)
国家自然科学基金面上项目(32072195)
浙江省杰出青年科学基金项目(LR23C200007)。
关键词
细菌素
诱导
群体感应
共培养
信号
bacteriocin
induction
quorum sensing
co-culture
signal
