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早期宫颈癌患者术后5年生存情况及预后影响因素研究 被引量:11

Survival Status and Prognosis Factors of Early Cervical Cancer
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摘要 目的 探讨早期宫颈癌患者术后5年生存状况及预后影响因素。方法 回顾性分析行手术治疗的148例早期宫颈癌患者的临床资料。分析早期宫颈癌患者术后5年生存状况及预后影响因素。结果 早期宫颈癌患者术后5年生存率为89.19%(132/148);单因素分析显示:国际妇产科联盟(FIGO)分期、肿瘤大小、肿瘤分化程度、淋巴结转移、肌层浸润深度、阴道切缘阳性与早期宫颈癌患者预后有关(P<0.05);年龄、病理类型、产次、术后辅助治疗与早期宫颈癌患者预后无关(P>0.05);多因素分析显示:FIGO分期Ⅱa期、肿瘤大小>4 cm、肿瘤低分化、淋巴结转移、肌层浸润深度≥1/2、阴道切缘阳性是影响早期宫颈癌患者预后的高危因素(P<0.05)。结论 早期宫颈癌患者术后五年生存率较高,受FIGO分期、肿瘤大小、肿瘤分化程度、淋巴结转移、肌层浸润深度、阴道切缘阳性等因素影响。 Objective To investigate the survival status and prognostic factors of early cervical cancer.Methods The clinical data of 148 patients with early cervical cancer were retrospectively analyzed.The 5-year postoperative survival status and prognostic factors of early cervical cancer patients were analyzed.Results The 5-year postoperative survival rate of early-stage cervical cancer patients was 89.19%(132/148);Univariate analysis showed that: the International Union of Obstetrics and Gynecology(FIGO) stage, tumor size, degree of tumor differentiation, lymph node metastasis, depth of myometrial invasion, and positive vaginal margin were related to the prognosis of early cervical cancer patients(P<0.05);Age, pathological type, birth grade, and postoperative adjuvant therapy were not associated with the prognosis of early-stage cervical cancer patients(P>0.05);Multivariate analysis showed that: FIGO stage a, tumor size>4 cm, low tumor-differentiation, lymph node metastasis, depth of myometrial invasion 1/2,and positive vaginal margin were the high risk factors affecting the prognosis of early cervical cancer patients(P<0.05).Conclusion Patients with early cervical cancer had high postoperative survival in five years, influenced by FIGO stage, tumor size, tumor differentiation, lymph node metastasis, depth of myometrial invasion, and positive vaginal margin.
作者 冯艳晓 贾书敏 FENG Yanxiao;JIA Shumin(The Third People's Hospital of Henan,Zhengzhou,450000)
出处 《实用癌症杂志》 2023年第1期36-38,共3页 The Practical Journal of Cancer
关键词 早期宫颈癌 生存状况 预后 影响因素 Early cervical cancer Survival condition Prognosis Influencing factors
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