摘要
目的探讨布地奈德混悬液雾化吸入治疗咽炎合并声带水肿的临床效果。方法30例咽炎合并声带水肿患者,采用随机数字表法分为参照组和研究组,各15例。参照组患者采用地塞米松治疗,研究组患者采用布地奈德混悬液雾化吸入治疗。比较两组患者治疗效果、治疗前后生活质量及治疗后不良反应(腹胀、恶心、腹泻)发生率与复发率。结果研究组治疗总有效率93.33%明显高于参照组的46.67%,差异具有统计学意义(P<0.05)。治疗前,两组躯体功能、物质功能、心理功能以及社会功能评分比较,差异无统计学意义(P>0.05);治疗后,研究组躯体功能评分(79.25±5.15)分、物质功能评分(79.34±5.29)分、心理功能评分(80.48±6.25)分以及社会功能评分(81.49±8.25)分均高于参照组的(70.44±5.22)、(70.49±5.14)、(70.21±1.25)、(70.25±6.25)分,差异具有统计学意义(P<0.05)。研究组治疗后不良反应发生率6.67%及复发率6.67%与参照组的26.67%、13.33%比较,差异无统计学意义(P>0.05)。结论布地奈德混悬液雾化吸入治疗咽炎合并声带水肿的效果优于地塞米松,可显著提升生活质量,并且可确保治疗安全性,促进患者良好预后。
Objective To discuss the clinical effect of budesonide suspension aerosol inhalation on pharyngitis with vocal cord edema.Methods A total of 30 patients with pharyngitis and vocal cord edema were randomly divided into the reference group and the research group,with 15 cases in each group.Patients in the reference group were treated with dexamethasone,and patients in the research group were treated with budesonide suspension aerosol inhalation.The therapeutic effect,quality of life before and after treatment,and incidence of adverse reactions(abdominal distension,nausea,diarrhea)and recurrence rate after treatment were compared between the two groups.Results The total effective rate of the research group was 93.33%,which was significantly higher than 46.67%in the reference group,and the difference was statistically significant(P<0.05).Before treatment,there was no statistically significant difference in scores of physical function,material function,psychological function and social function between the two groups(P>0.05).After treatment,the physical function score(79.25±5.15)points,material function score(79.34±5.29)points,psychological function score(80.48±6.25)points and social function score(81.49±8.25)points in the research group were higher than(70.44±5.22),(70.49±5.14),(70.21±1.25)and(70.25±6.25)points in the reference group,and the differences were statistically significant(P<0.05).After treatment,the incidence of adverse reactions and recurrence rate in the research group were 6.67%and 6.67%,and the differences were not statistically compared with 26.67%and 13.33%in the reference group(P>0.05).Conclusion Budesonide suspension aerosol inhalation is more effective than dexamethasone in the treatment of pharyngitis with vocal cord edema,and can significantly improve the quality of life of patients,ensure the safety of treatment,and promote the good prognosis of patients.
作者
周超
ZHOU Chao(Shangrao Municipal Hospital,Shangrao 334000,China)
出处
《中国现代药物应用》
2022年第24期129-131,共3页
Chinese Journal of Modern Drug Application
关键词
咽炎
声带水肿
布地奈德混悬液
地塞米松
Pharyngitis
Vocal cord edema
Budesonide suspension aerosol inhalation
Dexamethasone
