摘要
目的:分析重症脑出血患者术后发生颅内感染的影响因素。方法:选取2019年1月至2021年10月该院收治的116例重症脑出血患者进行前瞻性研究,按照术后是否发生颅内感染分为发生组和未发生组。对重症脑出血患者术后发生颅内感染的影响因素进行单因素和多因素分析。结果:116例重症脑出血患者术后发生颅内感染7例,占6.03%;发生组的性别、年龄、出血位置与未发生组比较,差异均无统计学意义(P>0.05);发生组引流管留置时间≥3 d、脑脊液渗漏、尿激酶应用次数≥3次、合并糖尿病、白蛋白水平<35 g/L占比均高于未发生组,差异有统计学意义(P<0.05);Logistic回归分析结果显示,引流管留置时间≥3 d、脑脊液渗漏、尿激酶应用次数≥3次、合并糖尿病、白蛋白水平<35 g/L均为重症脑出血患者术后发生颅内感染的危险因素(P<0.05)。结论:引流管留置时间≥3 d、脑脊液渗漏、尿激酶应用次数≥3次、合并糖尿病、白蛋白水平<35 g/L均为重症脑出血患者术后发生颅内感染的危险因素。
Objective:To analyze influencing factors of postoperative intracranial infection in patients with severe cerebral hemorrhage.Methods:A prospective study was conducted on 116 patients with severe cerebral hemorrhage admitted to the hospital from January 2019 to October 2021.They were divided into occurrence group and non-occurrence group according to whether intracranial infection occurred after the surgery.Logistic regression was used to analyze the influencing factors of postoperative intracranial infection in these patients with severe cerebral hemorrhage.Results:Intracranial infection occurred in 7 of the 116 patients with severe cerebral hemorrhage,accounting for 6.03%.There were no significant differences in gender,age and bleeding location between the two groups(P>0.05).The proportions of drainage tube indwelling time≥3 d,cerebrospinal fluid leakage,urokinase application times≥3 times,combined diabetes mellitus and albumin level<35 g/L in the occurrence group were higher than those in the non-occurrence group,and the differences were statistically significant(P<0.05).Logistic regression analysis showed that drainage tube indwelling time≥3 d,cerebrospinal fluid leakage,urokinase application times≥3 times,combined diabetes mellitus,albumin level<35 g/L were the risk factors of intracranial infection in the patients with severe cerebral hemorrhage after operation(P<0.05).Conclusions:Drainage tube indwelling time≥3 d,cerebrospinal fluid leakage,urokinase application times≥3 times,combined diabetes mellitus,albumin level<35 g/L are the risk factors of intracranial infection in the patients with severe cerebral hemorrhage after the surgery.
作者
宋海龙
SONG Hailong(Department of Neurosurgery of Huanghe Sanmenxia Hospital,Sanmenxia 472000 Henan,China)
出处
《中国民康医学》
2022年第22期1-3,共3页
Medical Journal of Chinese People’s Health
关键词
重症脑出血
颅内感染
穿刺引流术
术后
影响因素
Severe cerebral hemorrhage
Intracranial infection
Puncture drainage
Postoperative
Influencing factors
