摘要
目的分析凉山州4县HIV感染孕妇的临床特征及妊娠结局,为指导该地预防母婴传播工作提供依据。方法收集凉山州布拖、昭觉、越西、美姑4县2016年1月至2021年12月医疗机构发现的HIV感染且继续妊娠孕产妇资料,分析其流行病学特征和妊娠结局。结果共纳入分析5247例HIV感染孕产妇,平均年龄(29.48±5.39)岁,彝族占99.18%,90.05%为文盲/半文盲,75.80%在本次妊娠前已确诊HIV感染。90.53%产妇无孕产期异常情况,县级及以上助产机构分娩比例从2016年82.33%提高到2021年99.90%(χ_(趋势)^(2)=4.424,P<0.05),乡镇级助产机构分娩比例从2016年13.02%下降至2021年0(χ_(趋势)^(2)=4.356,P<0.05),人工破膜比例从2016年5.89%下降至2021年0.30%(χ_(趋势)^(2)=4.475,P<0.05)。死胎死产比例从2016年1.08%下降至2021年0(χ_(趋势)^(2)=4.549,P<0.05),早产发生率为8.25%。结论凉山州4县孕产妇HIV阳性检出率处较高水平,HIV感染孕产妇死胎死产比例不断下降,早产是HIV感染孕产妇常见不良妊娠结局。应加强孕产期保健服务能力建设,提升健康管理工作质量,并减少不良妊娠结局。
Objective To analyze the clinical characteristics and pregnancy outcomes of HIV-infected pregnant women in four counties of Liangshan Prefecture to provide a basis for preventing mother-to-child transmission in the area.Methods We collected data from HIV-infected pregnant women in Buto,Zhaojue,Yuexi,and Meigu counties of Liangshan Yi autonomous prefecture from January 2016 to December 2021 through National Management Information System for Prevention of Mother-to-child Transmission of HIV,Syphilis and Hepatitis B.Their epidemiological characteristics and pregnancy outcomes were analyzed.Results A total of 5247 HIV-infected pregnant women were included in the study,with an average age of(29.48±5.39).99.18%were Yi nationality,90.05%were illiterate/semiilliterate,and 75.80%infected HIV before pregnancy.90.53%of the pregnant women had no abnormal pregnancy and perinatal period.The proportion of births in midwifery institutions at the county level and above increased from 82.33%in2016 to 99.90%in 2021(χ_(trend)^(2)=4.424,P<0.05).The proportion of births in township health centers decreased from 13.02%in 2016 to 0 in 2021(χ_(trend)^(2)=4.356,P<0.05).The proportion of artificial rupture of membrane decreased from 5.89%in2016 to 0.30%in 2021(χ_(trend)^(2)=4.475,P<0.05).The proportion of stillbirth decreased from 1.08%in 2016 to 0 in 2021(χ_(trend)^(2)=4.549,P<0.05).The preterm birth rate was 8.25%.Conclusions The positive rate of HIV among pregnant women in four counties of Liangshan is at a high level.The proportion of stillbirths among HIV-infected pregnant women is decreasing.Preterm birth is a common adverse pregnancy outcome for HIV-infected pregnant women.It is necessary to strengthen the capacity construction of maternal and perinatal health care services,improve the quality of health management and reduce adverse pregnancy outcomes.
作者
张燕
张刚
王刚
张莉莉
岳岑
吴君梅
刘俐
马永娟
刘伟信
ZHANG Yan;ZHANG Gang;WANG Gang;ZHANG Lili;YUE Cen;WU Junmei;LIU Li;MA Yongjuan;LIU Weixin(Maternal and Child Health Hospital of Sichuan Province,Women and Children's Hospital of Sichuan Province,Women and Children's Hospital Affiliated to Chengdu Medical College,Chengdu 610045,Sichuan,China;Maternal and Child Health and Family Planning Service Center Liangshan,Xichang 615000,Sichuan)
出处
《中国艾滋病性病》
CAS
CSCD
北大核心
2022年第11期1272-1276,共5页
Chinese Journal of Aids & STD
基金
四川省医学会课题(Q20007)。
