摘要
采用高效液相色谱法测定婴幼儿用奶瓶中己内酰胺迁移量,并对其测定的结果进行不确定度的评估。参照JJF 1059.1—2012《测量不确定度评定与表示》和CNAS—GL 006:2019《化学分析中不确定度的评估指南》中的规定与要求,分析己内酰胺在测定过程中的各种不确定度来源。水基食品模拟物处理的样品中己内酰胺的迁移量测定结果为12.213 mg/L,其扩展不确定度为1.29 mg/L,结果表示为(12.21±1.29)mg/L,k=2;酸性食品模拟物处理的样品中己内酰胺的迁移量测定结果为15.608 mg/L,扩展不确定度为1.48 mg/L,结果表示为(15.61±1.48)mg/L,k=2;酒精类食品模拟物处理样品中己内酰胺所产生的迁移量测定结果为18.299 mg/L,扩展不确定度为1.84 mg/L,结果表示为(18.30±1.84)mg/L,k=2;油基食品模拟物处理样品中,己内酰胺的迁移量测定结果为10.232 mg/kg,扩展不确定度为0.99 mg/kg,结果表示为(10.23±0.99)mg/kg,k=2。通过评估发现,不确定度主要的影响因素是标准溶液的配制过程、仪器分析和样品重复性测量。
The uncertainty of the determination of caprolactam migration in baby bottle by high performance liquid chromatography(HPLC)was evaluated.According to the Provisions and Requirements in Evaluation and Expression of Measurement Uncertainty(JJF 1059.1–2012)and Guidance on Quantifying Uncertainty in Chemical Analysis(CNAS–GL 006:2019),the sources of various uncertainties in the determination process of caprolactam were analyzed.On water simulated fluid,the migration of caprolactam was 12.213 mg/L with the expanded uncertainty of 1.29 mg/L,the result was expressed as(12.21±1.29)mg/L,k=2.On acid simulated fluid,the migration of caprolactam was 15.608 mg/L with the expanded uncertainty of 1.48 mg/L,the result was expressed as(15.61±1.48)mg/L,k=2.On ethanol simulated fluid,the migration of caprolactam was 18.299 mg/L with the expanded uncertainty of 1.84 mg/L,the result was expressed as(18.30±1.84)mg/L,k=2.On oil simulated fluid,the migration of caprolactam was 10.232 mg/kg with the expanded uncertainty of 0.99 mg/kg,the result was expressed as(10.23±0.99)mg/kg,k=2.The main factors affecting the uncertainty are sample pretreatment,preparation of standard solution and linear fitting process of standard solution.
作者
杨芳
梁婷婷
YANG Fang;LIANG Tingting(Huaian Product Quality Supervision and Inspection Center,Huaian 223001,China)
出处
《化学分析计量》
CAS
2022年第11期90-94,共5页
Chemical Analysis And Meterage
