摘要
目的:探讨彩色多普勒超声检查下,原发性高血压和颈动脉粥样硬化的相关性。方法:选取2021年1月-2021年12月我院收治的原发性高血压患者,共230例。患者均应用彩色多普勒超声检测检查,根据颈动脉超声检查结果分为两组,观察组(n=129)颈动脉粥样硬化;对照组(n=101)颈动脉正常。分别行动态血压检测和血液生化检查,比较两组患者的基线资料[年龄、性别、体质指数、谷丙转氨酶(Alt)、血小板计数(plt)、谷草转氨酶(Ast)、血糖(GLU)、甘油三酯(TG)、总胆固醇(Tch)、低密度脂蛋白胆固醇(Ldl)、高密度脂蛋白胆固醇(Hdl)、血清超敏C反应蛋白(hs-CRP)、尿酸(UA)、同型半胱氨酸(Hcy)],BPV指标[24h平均收缩压(24hSBP)、夜间平均收缩压(nSBP)、日间平均收缩压(dSBP)、24h平均舒张压(24hDBP)、夜间平均舒张压(nDBP)、日间平均舒张压(dDBP),24h舒张压变异系数(24hDCV)、24h收缩压变异系数(24h SCV)、夜间收缩压变异系数(nSCV)、日间收缩压变异系数(dSCV)、夜间舒张压变异系数(nDCV)、日间舒张压变异系数(dDCV)],对可能造成原发性高血压患者颈动脉粥样硬化的因素进行分析,采用Logistic回归分析多因素对原发性高血压患者颈动脉粥样硬化的影响。结果:两组患者的性别、Ast、Alt、Hdl、UA、Hcy比较无明显差异(均P>0.05);观察组患者年龄、GLU、hs-CRP、dSBP、24hSBP、nSBP、dDBP、24hDBP、nDBP、24hDCV、24hSCV、nSCV、dSCV、nDCV、dDCV均明显高于对照组,体质指数、TG、Plt、Ldl、Tch均明显低于对照组(均P<0.05)。多因素Logistic回归分析相关结果显示,年龄、TG、hs-CRP、24hSCV、24hSBP均是原发性高血压患者发生颈动脉粥样硬化的独立危险因素(OR=1.677、1.554、1.750、1.593、1.268,P=0.000、0.000、0.000、0.001、0.003)。结论:年龄、TG、血清hs-CRP、Hcy、UA、24hSBP、24hSCV是造成原发性高血压患者颈动脉粥样硬化的独立危险因素,建议尽早采用彩色多�
Objective:To explore the correlation between essential hypertension and carotid atherosclerosis by color Doppler ultrasound.Methods:From January 2021 to December 2021,230 patients with essential hypertension were selected.Color Doppler ultrasound was used in both groups.The patients in both groups were examined by color Doppler ultrasound.According to the results of carotid ultrasound examination,they were divided into two groups:the observation group(n=129)had carotid atherosclerosis;the control group(n=101)had normal carotid arteries.Flow blood pressure measurement and blood biochemical examination were performed respectively.The baseline data of the two groups were compared[lanine aminotransferase(ALT),PLT,aaspartate aminotransferase(AST),blood glucose(Glu),riglycerides(TG),total cholesterol(TCH),low-density lipoprotein cholesterol(LDL),thigh-density lipoprotein cholesterol(HDL),serum high-sensitivity C-reactive protein(hs-CRP),uric acid(UA),homocysteine(Hcy)],BPV indicators[24-hour mean systolic blood pressure(24hSBP),nighttime mean systolic blood pressure(nSBP),24-hour mean diastolic blood pressure(24hDBP),daily mean systolic blood pressure(dSBP),daytime mean diastolic blood pressure(dDBP),nighttime mean diastolic blood pressure(nDBP),24-hour diastolic variation coefficient(24hDCV),24-hour systolic blood pressure variation coefficient(24hSCV),nighttime systolic blood pressure variation coefficient(nscv),daytime systolic blood pressure variation coefficient(24hDCV),nocturnal diastolic coefficient of variation(nDCV)and daytime diastolic variation coefficient(dDCV)],and analyze the factors that may cause carotid atherosclerosis in hypertensive patients.Logistic regression was used to analyze the influence of various factors on carotid atherosclerosis in hypertensive patients.Results:There were no obvious differences in gender,Ast,Alt,Hdl,UA and Hcy between the two groups(all P>0.05).The age,GLU,hs-CRP,dSBP,24hSBP,nSBP,dDBP,24hDBP,nDBP,24hDCV,24hSCV,nSCV,dSCV,nDCV and dDCV of the test group were obviously higher
作者
沈冬英
SHEN Dong-ying(Department of Ultrasound,Suzhou Ninth People's Hospital,Jiangsu 215200,China)
出处
《影像技术》
CAS
2022年第6期15-20,共6页
Image Technology
