摘要
冠心病是2型糖尿病的主要并发症,也是2型糖尿病患者死亡的重要原因,延缓2型糖尿病患者动脉粥样硬化的进展成为提高人类生活质量的紧迫问题。C1q肿瘤坏死因子相关蛋白9(CTRP9)作为心血管保护因子,在延缓2型糖尿病相关动脉粥样硬化的进展中发挥什么作用,是目前学术界研究的热点。本综述总结了CTRP9在2型糖尿病相关动脉粥样硬化中作用的最新进展,重点介绍其在2型糖尿病相关动脉粥样硬中的作用机制,为预防及治疗糖尿病相关动脉粥样硬化提供新的思路及解决方法。
Coronary atherosclerotic heart disease is not only a major complication of type 2 diabetes mellitus but also an important cause of death in patients with this condition.Delaying the progress of atherosclerosis in patients with type 2 diabetes mellitus has become an urgent issue to improve human life quality.Accumulated evidence suggests that C1 q tumor necrosis factor-related protein 9(CTRP9)could play a role in preventing the progression of type 2 diabetes-related atherosclerosis.In this review,we summarize the latest progress in the role of CTRP9 in type 2 diabetes-related atherosclerosis,focusing on its mechanism in type 2 diabetes-related atherosclerosis to provide new ideas and solutions for the prevention and treatment of diabetes-related atherosclerosis.
作者
马雅楠
金晓雪
刘德敏
谷国强
MA Ya'nan;JIN Xiaoxue;LIU Demin;GU Guoqiang(Department of Cardiology,The Second Hospital of Hebei Medical University.Shijiazhuang,050000,China)
出处
《临床心血管病杂志》
CAS
北大核心
2022年第10期833-837,共5页
Journal of Clinical Cardiology
基金
河北省自然科学基金精准医学联合基金重点项目(No:H2020206409)
河北省自然科学基金资助项目(No:H2021206220)。
