摘要
目的探讨醒脑静注射液联合丁苯酞软胶囊治疗后循环缺血性眩晕(PCIV)患者的效果及对后循环血流速度的影响。方法选取2020年10月-2021年11月收治的PCIV 93例,根据治疗方法不同将其分为观察组(47例)和对照组(46例)2组。观察组给予醒脑静注射液联合丁苯酞软胶囊治疗,对照组给予醒脑静注射液治疗。比较2组治疗后临床效果,治疗前后眩晕相关评分[眩晕评估评分量表(DARS)和眩晕障碍调查表(DHI)]和后循环血流速度(基底动脉、左椎动脉和右椎动脉),以及治疗期间不良反应发生情况。结果治疗后,观察组总有效率高于对照组(P<0.05)。治疗后,DARS和DHI评分2组均较治疗前降低,且观察组低于对照组(P<0.01);基底动脉、左椎动脉和右椎动脉血流速度2组均较治疗前增快,且观察组快于对照组(P<0.05,P<0.01)。治疗期间,2组总不良反应发生率比较差异无统计学意义(P>0.05)。结论醒脑静注射液联合丁苯酞软胶囊治疗PCIV患者可提高临床效果,改善眩晕症状,增加椎-基底动脉血供,且安全性良好。
Objective To investigate the effect of Xingnaojing injection combined with Butylphthalide soft capsule in the treatment of posterior circulation ischemic vertigo(PCIV)and its influence on posterior circulation blood flow velocity.Methods A total of 93 patients with PCIV admitted from October 2020 to November 2021 were selected and divided into the observation group(n=47)and the control group(n=46)according to different treatment methods.The observation group was treated with Xingnaojing injection combined with Butylphthalide soft capsule,and the control group was treated with Xingnaojing injection.The clinical effects,vertigo related scores[dizziness assessment rating scale(DARS)and dizziness handicap inventory(DHI)]and posterior circulation blood flow velocity(basilar artery,left vertebral artery and right vertebral artery)before and after treatment as well as adverse reactions during treatment were compared between the two groups.Results After treatment,the total effective rate of the observation group was higher than that of the control group(P<0.05).After treatment,the DARS and DHI scores in both groups were lower than those before treatment,and lower in the observation group than in the control group(P<0.01).The blood flow velocity of basilar artery,left vertebral artery and right vertebral artery in the two groups were faster than that before treatment,and faster in the observation group than in the control group(P<0.01,P<0.05).During treatment,there was no significant difference in the total adverse reaction rate between the two groups(P>0.05).Conclusion Xingnaojing injection combined with Butylphthalide soft capsule can improve the clinical effect,relieve vertigo symptoms,and increase the blood supply of vertebral basilar artery in patients with PCIV,with good safety.
作者
李佳佳
韩慧儒
王玉琳
刘晶
LI Jia-jia;HAN Hui-ru;WANG Yu-lin;LIU Jing(Department of Neurology,the First Hospital of Qinhuangdao City,Qinhuangdao,Hebei 066000,China)
出处
《临床误诊误治》
CAS
2022年第10期38-41,91,共5页
Clinical Misdiagnosis & Mistherapy
关键词
眩晕
醒脑静注射液
丁苯酞软胶囊
眩晕评分
血流速度
药物毒性
Vertigo
Xingnaojing injection
Butylphthalide soft capsule
Vertigo score
Blood flow velocity
Drug toxicity
