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骨折术后深静脉血栓形成合并肺栓塞的相关因素分析 被引量:5

Analysis of related factors of PE in patients with deep venous thrombosis after fracture surgery
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摘要 目的 探讨骨折术后深静脉血栓形成病人合并肺栓塞(PE)的相关因素。方法 2019年1月~2021年7月在我院就诊的骨折术后深静脉血栓病人130例,分析PE发生情况,比较并发PE和无PE病人临床资料的差异,分析发生PE的影响因素。结果 PE发生率为19.23%;并发PE病人年龄≥60岁、吸烟、糖尿病、恶性肿瘤比例明显高于无PE病人,差异有统计学意义(P<0.05);并发PE病人D-二聚体高于无PE病人,差异有统计学意义(P<0.05);Logistic回归分析显示,年龄、吸烟、恶性肿瘤是深静脉血栓并发PE的影响因素(OR=2.199、2.469和2.779,P<0.05)。Logistic回归方程预测PE的ROC曲线下面积为0.811(P<0.05),其灵敏性和特异性分别为83.00%和80.00%。结论 年龄、吸烟及恶性肿瘤是骨折术后深静脉血栓并发PE的危险因素。 Objective To explore the related factors of pulmonary embolism(PE) in patients with deep venous thrombosis after fracture surgery.Methods 130 patients with deep venous thrombosis after fracture surgery treated in our hospital from January 2019 to July 2021 were retrospectively selected to analyze the incidence of PE and compare the clinical data of patients with and without PE,the influencing factors of PE were analyzed.Results The incidence of PE was 19.23%.The proportion of patients with concurrent PE,age over 60 years, smoking, diabetes and malignancy were significantly higher than those without PE(P<0.05).The D-dimer in patients with PE was significantly higher than that in patients without PE(P<0.05).Logistic regression analysis showed that age, smoking and malignant tumor were the influencing factors of deep venous thrombosis complicated with PE(OR=2.199,2.469 and 2.779,P<0.05).Logistic regression equation predicted that the area under the ROC curve of PE was 0.811,P<0.05,and its sensitivity and specificity were 83.00% and 80.00% respectively.Conclusion Deep venous thrombosis complicated with PE after fracture surgery is affected by patients’ age, smoking and malignant tumor, which is worthy of clinical attention.
作者 刘晗 王小虎 LIU Han;WANG Xiaohu(Hanchuan People's Hospital,Xiaogan,Hubei 431400,China;不详)
出处 《临床外科杂志》 2022年第9期890-892,共3页 Journal of Clinical Surgery
关键词 骨折 深静脉血栓 肺栓塞 影响因素 fracture deep venous thrombosis pulmonary embolism influence factor
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