摘要
目的探讨对精神分裂症患者采取利培酮片与阿立哌唑片维持治疗的效果及药理学研究。方法选取2019年4月至2020年4月在辽宁省沈阳市精神卫生中心治疗的80例精神分裂症患者,随机分为利培酮组和阿立哌唑组,对两组患者采用临床常规的护理治疗方法,阿立哌唑组40例精神分裂症患者采取阿立哌唑干预治疗方法,利培酮组40例精神分裂症患者采取利培酮干预治疗方法,比较两组患者接受护理治疗后患者临床有效率比较。结果利培酮组患者接受治疗后患者临床有效率92.50%,高于阿立哌唑组患者的77.50%,差异有统计学意义(P<0.05)。结论对精神分裂症患者来说,采取阿立哌唑治疗的临床效果较好,可以有效改善精神分裂症患者情况并能改善状态。
Objective To compare the efficacy of risperidone tablets and aripiprazole tablets in the maintenance treatment of patients with schizophrenia and to study the pharmacology.Methods Eighty patients with schizophrenia in Shenyang Mental Health Center from April 2019 to April 2020 were randomly divided into risperidone group and aripiprazole group.Clinical routine nursing treatment was used for the two groups,and 40 patients with schizophrenia in aripiprazole group were treated with aripiprazole intervention.In risperidone group,40 patients with schizophrenia were treated with risperidone intervention.Results The clinical effective rate of risperidone group was 92.5%after treatment,which was higher than that of aripiprazole group(77.5%),and the difference was statistically significant(P<0.05).Conclusion For patients with schizophrenia,the clinical effect of aripiprazole treatment is better,which can effectively improve the condition and state of patients with schizophrenia.
作者
李菁
LI Jing(Department of Drug Administration,Shenyang Mental Health Center,Shenyang 110168,China)
出处
《中国医药指南》
2022年第35期65-68,共4页
Guide of China Medicine
关键词
精神分裂症
利培酮
阿立哌唑
临床疗效
Schizophrenia
Risperidone
Aripiprazole
Clinical efficacy
