摘要
左旋肉碱作为人体中不可或缺的成分,具有重要的生理作用,在线粒体脂肪酸代谢和ATP产生过程中发挥重要作用。在缺乏状态下,线粒体功能受损、细胞代谢改变,影响机体多个系统的功能,进而引发多种疾病。外源性补充左旋肉碱不仅可以缓解代谢紊乱和肉碱缺乏症相关的疾病状态,还可以帮助机体恢复肉碱稳态、保持新陈代谢、能量平衡和健康状况。文章通过对既往文献的回顾,对左旋肉碱在各类疾病中的用途进行总结,以提高临床医生对左旋肉碱的认识。
As an indispensable component in the humanbody,L-carnitine has important physiological functions andplays an important role in mitochondrial processes,fatty acidmetabolism and ATP production. In the state of deficiency,mitochondrial function is damaged,cell metabolism ischanged,and the functions of multiple systems in the body areaffected,which in turn leads to the emergence of its variousdiseases. Exogenous L-carnitine supplementation can not onlyrelieve metabolic disorders and disease state related tocarnitine deficiency,but also help the body restore carnitinebalance and maintain metabolism,energy balance and health.This article summarizes the use of L-carnitine in variousdiseases by reviewing the previous literature,in order toimprove clinicians’ understanding of L-carnitine.
作者
张会丰
赵婉晴
ZHANG Hui-feng;ZHAO Wan-qing(Department of Pediatrics,the Second Hospital of Hebei Medical University,Shijiazhuang 050000,China)
出处
《中国实用儿科杂志》
CSCD
北大核心
2022年第10期754-758,共5页
Chinese Journal of Practical Pediatrics
关键词
左旋肉碱
缺乏
疾病
L-carnitine
deficiency
disease
