摘要
目的探讨超声检测胎儿大脑中动脉、脐动脉血流参数诊断胎儿发生宫内窘迫的价值。方法选取2019年10月至2021年12月在香港大学深圳医院产检并分娩的160例孕妇作为研究对象,根据是否发生胎儿宫内窘迫分为窘迫组(有宫内窘迫,80例)和对照组(无宫内窘迫,80例),两组均接受超声检查,比较两组胎儿的大脑中动脉、脐动脉血流参数指标,根据出生后Apgar评分将新生儿缺氧程度分为轻度、重度并分层比较大脑中动脉、脐动脉血流参数指标,采用线性相关分析法分析大脑中动脉、脐动脉血流参数与Apgar评分的相关性。结果窘迫组胎儿的大脑中动脉阻力指数(RI)、搏动指数(PI)、收缩期峰值/舒张期峰值血流速度(S/D)值均低于对照组,差异有统计学意义(P<0.05);窘迫组胎儿的脐动脉RI、PI、S/D值均高于对照组,差异有统计学意义(P<0.05)。大脑中动脉RI、PI、S/D值诊断胎儿宫内窘迫的曲线下面积(AUC)分别为0.779、0.863、0.778;脐动脉RI、PI、S/D值诊断胎儿宫内窘迫的AUC分别为0.794、0.844、0.750。重度缺氧组胎儿的大脑中动脉RI、PI、S/D值均高于轻度缺氧组,差异有统计学意义(P<0.05);重度缺氧组胎儿的脐动脉RI、PI、S/D值均低于轻度缺氧组,差异有统计学意义(P<0.05)。窘迫组胎儿的大脑中动脉RI、PI、S/D值与新生儿出生后1 min Apgar评分呈正相关(P<0.05);窘迫组胎儿的脐动脉RI、PI、S/D值与新生儿出生后1 min Apgar评分呈负相关(P<0.05)。结论超声检测胎儿大脑中动脉、脐动脉血流参数变化可诊断宫内窘迫的发生,并且与新生儿缺氧程度有关。
Objective To investigate the value of ultrasonography detection of fetal middle cerebral artery and umbilical artery blood flow parameters and fetal distress in utero.Methods A total of 160 pregnant women who gave birth in Shenzhen Hospital of the University of Hong Kong from October 2019 to December 2021 were selected as the research objects.According to whether intrauterine distress occurred,the patients were divided into distress group(with intrauterine distress,80 cases)and control group(without intrauterine distress,80 cases).Both groups were examined by ultrasound.Blood flow parameters of middle cerebral artery and umbilical artery were compared between the two groups.According to the Apgar score,the degree of neonatal hypoxia was divided into mild and severe,and the blood flow parameters of middle cerebral artery and umbilical artery were stratified and compared.The correlation between the blood flow parameters of middle cerebral artery and umbilical artery and Apgar score was analyzed by linear correlation analysis.Results The middle cerebral artery resistance index(RI),pulsatility index(PI)and peak systolic/diastolic blood flow velocity(S/D)values of fetuses in the distress group were lower than those in the control group,and the differences were statistically significant(P<0.05).The umbilical artery RI,PI and S/D values of the fetuses in the distress group were higher than those in the control group,and the differences were statistically significant(P<0.05).The area under the curve(AUC)of RI,PI and S/D values in the diagnosis of fetal distress were 0.779,0.863 and 0.778,respectively.The AUC of umbilical artery RI,PI and S/D in the diagnosis of fetal distress were 0.794,0.844 and 0.750,respectively.The RI,PI and S/D values of middle cerebral artery in severe hypoxia fetuses were higher than those in mild hypoxia fetuses,and the differences were statistically significant(P<0.05).The umbilical artery RI,PI and S/D values of severe hypoxia fetuses were lower than those of mild hypoxia fetuses,and the differ
作者
熊初琴
王磊
刘镭
农丽录
林胜谋
XIONG Chuqin;WANG Lei;LIU Lei;NONG Lilu;LIN Shengmou(Department of Nursing,Shenzhen Hospital of the University of Hong Kong,Guangdong Province,Shenzhen 518000,China)
出处
《中国当代医药》
CAS
2022年第31期144-148,共5页
China Modern Medicine
关键词
超声
胎儿
大脑中动脉
脐动脉
血流参数
宫内窘迫
Ultrasound
Fetus
Middle cerebral artery
Umbilical artery
Blood flow parameters
Intrauterine distress
