摘要
目的:探究小儿牛黄清心散对脓毒症脑病脑损伤的保护作用。方法:选取2016年7月-2020年6月在赣南医学院第一附属医院住院且确诊为脓毒症脑病的患儿50例,随机分为对照组和治疗组,对照组予以常规治疗,治疗组在常规治疗的基础上加用小儿牛黄清心散,观察并比较两组患儿治疗后的退热时间、血浆降钙素原(PCT)含量、神经元特异性烯醇化酶(NSE)含量、Glasgow意识障碍昏迷评定量表(GCS)评分以及脑电图(EEG)。结果:与对照组相比,治疗组患儿的退热时间更短,PCT含量、NSE含量更低,GCS评分更高,EEG疗效更佳,差异均有统计学意义(P<0.05)。结论:在常规治疗的基础上,加用小儿牛黄清心散能够有效缩短脓毒症脑病患儿的发热时间,控制炎症反应,保护脑神经。
Objective:To explore the protective effect of Xiaoer Niuhuang Qingxin Powder on brain injury caused by septic encephalopathy.Methods:A total of 50 children with septic encephalopathy hospitalized in The First Affiliated Hospital of Gannan Medical University from July 2016 to June 2020 were randomly divided into control group and treatment group.The control group was treated with routine treatment.The treatment group was treated with Xiaoer Niuhuang Qingxin Powder on the basis of routine treatment.The antipyretic time,PCT content,NSE content,GCS score and EEG of the two groups were observed and compared.Results:Compared with the control group,the antipyretic time of children in the treatment group was shorter,PCT content and NSE content were lower,GCS score was higher,and EEG effect was better,with statistical significance(P<0.05).Conclusion:On the basis of routine treatment,the addition of Xiaoer Niuhuang Qingxin Powder can effectively shorten the fever time ofchildren with septic encephalopathy,controlinflammatory reaction and protect cerebral nerves.
作者
饶兴愉
刘华之
胡超华
罗开源
邓国平
RAO Xing-yu;LIU Hua-zhi;HU Chao-hua;LUO Kai-yuan;DENG Guo-ping(The First Affiliated Hospital of Gannan Medical University;The Third Affiliated Hospital of Gannan Medical University,Ganzhou,Jiangxi 341000)
出处
《赣南医学院学报》
2022年第8期809-812,共4页
JOURNAL OF GANNAN MEDICAL UNIVERSITY
基金
江西省卫生健康委员会科技计划项目(编号:20195400)
赣南医学院重点扶持项目(编号:ZD201832)。
关键词
小儿牛黄清心散
脓毒症脑病
脑损伤
儿童
Xiaoer Niuhuang Qingxin Powder
Septic encephalopathy
Brain injury
Child
