摘要
肾病综合征(nephrotic syndrome,NS)是表现为肾小球滤过屏障受损的一组临床症候群,蛋白尿是该病最基本的临床表现。足细胞损伤与肾病综合征的发生和发展密切相关。该文就足细胞损伤机制与以足细胞损伤为主要病理表现的膜性肾病、局灶节段性肾小球硬化、微小病变型肾病所致肾病综合征的关系以及中药干预的途径做一简单综述,为中医药防治肾病综合征拓展新思路。
Nephrotic syndrome(NS)is a group of clinical syndromes characterized by impaired glomerular filtration barrier,and proteinuria is the most basic clinical manifestation of this disease.Podocyte injury is closely related to the occurrence and development of nephrotic syndrome.This article briefly reviews the relationship between the mechanism of podocyte injury and nephrotic syndrome caused by membranous nephropathy,focal segmental glomerulosclerosis,and minimal change nephropathy with podocyte injury as the main pathological manifestation,as well as the ways of traditional Chinese medicine intervention.,to develop new ideas for the prevention and treatment of nephrotic syndrome with traditional Chinese medicine.
作者
谢雨涵
王圣治
XIE Yuhan;WANG Shengzhi(Liaoning University of Traditional Chinese Medicine,Liaoning Shenyang 110032,China;Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Liaoning Shenyang 110847,China)
出处
《中医药临床杂志》
2022年第9期1763-1767,共5页
Clinical Journal of Traditional Chinese Medicine
基金
沈阳市科学技术计划公共卫生研发专项(20-205-4-030)。
关键词
肾病综合征
足细胞损伤
膜性肾病
局灶节段性肾小球硬化
微小病变型肾病
中药
Nephrotic syndrome
Podocyte injury
Membranous nephropathy
Focal segmental glomerulosclerosis
Minimal change nephropathy
Traditional Chinese medicine
