摘要
目的探讨梗阻性肾病及慢性肾炎所致肾功能衰竭危险因素及病理特点。方法选取2012年9月至2014年9月东莞市桥头医院收治的梗阻性肾病患者97例,其中36例合并肾功能衰竭,记为A组;选取慢性肾炎患者91例,34例合并肾衰功能竭,记为B组,观察两组患者血肌酐(Scr)、血红蛋白(Hb)、肾小球滤过率(GFR),分析梗阻性肾病及慢性肾炎所致肾功能衰竭危险因素。结果 A组Scr为(587.63±121.06)μmol/L,低于B组的(986.24±241.53)μmol/L,Hb、GFR分别为(93.35±12.05)g/L、(19.63±8.85)ml/min,较B组高,差异有统计学意义(P<0.05)。年龄≥45岁、用药依从性低、梗阻时间≥6周是梗阻性肾病肾功能衰竭的危险因素;年龄≥45岁、合并高血压、用药依从性低是慢性肾炎致肾功能衰竭危险因素。结论慢性肾炎所致肾功能衰竭病情进展较梗阻性肾病致肾功能衰竭快;慢性肾炎所致肾功能衰竭可能与高血压、年龄、用药依从性有关,梗阻性肾病致肾功能衰竭与年龄、用药依从性、梗阻时间有关。
Objective To investigate the risk factors of kidney failure caused by obstructive nephropathy and chronic nephritis and analyze its pathological characteristics. Methods From September 2012 to September 2014,ninety-seven patients with obstructive nephropathy treated in Qiaotou hospital of Dongguan were selected,among whom 36 patients combined with kidney failure as group A; and 91 patients with chronic nephritis were selected,among whom 34 cases combined with kidney failure as group B. The Serum creatinine（ Scr）,hemoglobin（ Hb） and glomerular filtration rate（ GFR） in the two groups were observed and risk factors of kidney failure caused by obstructive nephropathy and chronic nephritis were analyzed. Results The Scr in patients of group A was（ 587. 63 ± 121. 06） μmol / L,which was lower than that in group B [（ 986. 24 ± 241. 53） μmol / L]. Hb and GFR levels in group A were respectively（ 93. 35 ± 12. 05） g / L and（ 19. 63 ± 8. 85） ml / min,which were higher than those in group B,the differences were insignificant（ P〈0. 05）. The medication compliance of the patients over 45 years old was low and the obstruction time longer than or equal to six weeks was the risk factor for obstructive nephropathy and kidney failure. The low medication compliance of the patients more than or equal to 45 years of age and with high blood pressure were the risk factors of kidney failure caused by chronic nephritis. Conclusion Kidney failure caused by chronic nephritis progresses faster than kidney failure caused by obstructive nephropathy. Kidney failure caused by chronic nephritis may be correlated with high blood pressure,age and medication compliance. Kidney failure caused by obstructive nephropathy may be correlated with age,medication compliance and the obstruction time.
出处
《临床医学》
CAS
2015年第10期4-6,共3页
Clinical Medicine
关键词
肾功能衰竭
梗阻性肾病
慢性肾炎
病理特点
危险因素
Kidney failure
Obstructive nephropathy
Chronic nephritis
Pathological characteristics
Risk factors
