摘要
记忆T细胞(TM)是原发免疫中产生的细胞,可对先前遇到的病原体或抗原保留长时间响应,快速有效地产生继发免疫应答。TM可分为中央记忆T细胞(TCM)、效应记忆T细胞(TEM)和干细胞样记忆性T细胞(TSCM)。认识和研究TM的不同亚群、功能特征及调控因素有利于临床上更好地认识自身免疫性疾病,为其治疗提供新的思路。
Memory T cells(TM)are cells produced in primary immunity,which can retain a long-term response to previously encountered pathogens or antigens,and effectively and rapidly produce secondary immune responses. TM are roughly divided into central memory T cells(TCM),effector memory T cells(TEM)and stem cell memory T cells(TSCM). Recognizing and studying different subgroups,functional characteristics and regulatory factors of TM are conducive to a better understanding of autoimmune diseases clinically and provides new ideas for treatment.
作者
付姿
瞿文(指导)
FU Zi;QU Wen(Department of Hematology,General Hospital of Tianjin Medical University,Tianjin 300052,China)
出处
《中国免疫学杂志》
CAS
CSCD
北大核心
2022年第18期2280-2283,共4页
Chinese Journal of Immunology
基金
国家自然科学基金项目(81970116,81770118)。
