摘要
目的探讨分析减重手术治疗肥胖合并非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)的效果。方法通过电脑随机抽选的方式选取2020年1月—2021年6月在湖北省黄石市爱康医院接受治疗的肥胖合并非酒精性脂肪性肝病患者80例作为研究对象,将其分为两组,各40例;观察组采用腹腔镜袖状胃切除术(laparoscopic sleeve gastrectomy,LSG)进行治疗,对照组采用腹腔镜Roux-en-Y胃旁路术(laparoscopic Roux-en-Y gastric bypass,LRYGB)进行治疗。对比两组患者糖脂代谢情况、NAFLD改善情况、肥胖改善情况、临床指标、生活质量及并发症发生率。结果手术前后,两组各项糖脂代谢指标情况比较,差异无统计学意义(P>0.05);术后两组患者的各项糖脂代谢指标水平较术前均有明显改善,差异有统计学意义(P<0.05)。手术前后,两组NAFLD改善情况比较,差异无统计学意义(P>0.05);术后两组患者的NAFLD改善情况优于术前,差异有统计学意义(P<0.05)。手术前后,两组患者的肥胖情况比较,差异无统计学意义(P>0.05);术后两组患者肥胖情况的各项指标较术前明显降低,差异有统计学意义(P<0.05)。观察组的各项临床指标均小于对照组,差异有统计学意义(P<0.05)。手术前后,两组患者的生活质量水平比较,差异无统计学意义(P>0.05);术后两组患者的生活质量水平明显高于术前,差异有统计学意义(P<0.05)。观察组并发症发生率为2.50%,较对照组的22.50%更低,差异有统计学意义(χ^(2)=7.314,P<0.05)。结论对于肥胖合并非酒精性脂肪性肝病的患者,通过LSG和LRYGB减重手术的方式进行治疗,都能获得一定成效,并且两种方法的治疗效果相似,患者的生活质量和身体健康情况有理想好转,应将其应用在临床实际中并进行推广。
Objective To explore and analyze the effect of bariatric surgery in the treatment of obesity with nonalcoholic fatty liver disease(NAFLD).Methods 80 obese patients with nonalcoholic fatty liver disease who were treated in Huangshi Aikang Hospital in Hubei Province from January 2020 to June 2021 were selected by computer random selection as the research subjects,and divided into two groups,with 40 cases in each group.The observation group treated with laparoscopic sleeve gastrectomy(LSG)and the control group treated with laparoscopic Roux-en-Y gastric bypass(LRYGB).The glucose and lipid metabolism,NAFLD improvement,obesity improvement,clinical indicators,quality of life and complication rate were compared between the two groups.Results There was no statistically significant difference between the two groups before and after operation(P>0.05);the levels of glucose and lipid metabolism indexes in the two groups after operation were significantly improved compared with those before operation,and the difference was statistically significant(P<0.05).There was no statistically significant difference in the improvement of NAFLD between the two groups before and after operation(P>0.05);the improvement of NAFLD in the two groups after operation was better than that before operation,and the difference was statistically significant(P<0.05).There was no statistically significant difference in obesity between the two groups before and after operation(P>0.05);the indexes of obesity in the two groups after operation were significantly lower than those before operation,and the difference was statistically significant(P<0.05).The clinical indexes of the observation group were less than those of the control group,and the difference was statistically significant(P<0.05).There was no statistically significant difference in the quality of life between the two groups before and after operation(P>0.05);the quality of life of the two groups after operation was significantly higher than that before operation,and the difference was statist
作者
李燕
何韵彬
LI Yan;HE Yunbin(Department of General Surgery,Huangshi Aikang Hospital,Huangshi,Hubei Province,435000 China)
出处
《中外医疗》
2022年第17期52-56,共5页
China & Foreign Medical Treatment
