摘要
目的:挖掘毛德西教授治疗眩晕(高血压病)的新处方。方法:根据“K-聚类分析”和跟师学习,使用WPS软件录入数据,分析用药频数、四气、五味、归经及功效,使用SPSS 26.0软件的“聚类分析”功能得出新处方。结果:筛选出355首处方,涉及234味中药,用药总频数为4624;用药频数大于50的有桑叶、杜仲叶、天麻、荷叶、绞股蓝、罗布麻叶、银杏叶、赤芍、丹参等,以上药物四气统计结果为寒性药945次,平性药808次,温性药436次等;五味统计结果为苦味药1963次,甘味药1427次,辛味药637次等;归经统计结果为肝经1848次,肺经855次,心经818次,脾经795次,胃经760次,肾经329次等;功效统计结果为平肝息风药489次,活血化瘀药394次,补气药370次,发散风热药359次等;高频用药“K-聚类分析”得出两组药物,第1组:桑叶、杜仲叶、天麻、荷叶、绞股蓝、罗布麻叶、银杏叶、赤芍、丹参;第2组:白术、茯苓、半夏、黄连、葛根、麦冬、蔓荆子、牛膝、石菖蒲、决明子、茺蔚子、郁金、甘草、钩藤。结论:毛德西教授治疗眩晕(高血压病)用药四气以寒性和平性为主;用药五味以苦、甘、辛为主;用药归经以肝经、肺经、心经、脾经、胃经为主;用药功效以平肝息风,活血化瘀为主,其次是发散风热,补气化痰。
Objective:To explore the potential prescription of Professor MAO Dexi for the treatment of vertigo(hypertension).Methods:Based on learning from the professor and“K-cluster analysis”,WPS software was used to input data to analyze the medication frequency,medicinal properties,medicinal tastes,meridian tropism and efficacy,and the cluster analysis feature of SPSS26.0 software was used to obtain new prescription.Results:Three hundred and fifty-five prescriptions were screened out,involving 234 TCM medicines,and the total medication frequency was 4624 times.The medication frequencies more than 50 times were listed as follows:Sangye(Folium Mori),Duzhong Ye(Folium Eucommiae),Tianma(Gastrodiae Rhizoma),Heye(Lotus Leaf),Jiaogulan(Gynostemma pentaphyllum),Luobuma Ye(Apocynum Venetum L.),Yinxing Ye(Folium Ginkgo),Chishao(Radix Paeoniae Rubra),Danshen(Radix Paeonia Rubra),etc..The statistical results of the medicinal properties of the above-mentioned medicines were as follows:945 times of cold medicine,808 times of moderate medicine,436 times of warm medicine,etc..The statistical results of medicinal tastes were as follows:1963 times of bitter medicine,1427 times of sweet medicine,637 times of pungent medicine,etc..The statistical results of meridian tropism were as follows:1848 times of liver meridian,855 times of lung meridian,818 times of heart meridian,795 times of spleen meridian,760 times of stomach meridian,329 times of kidney meridian,etc..The statistical results of efficacy were as follows:489 times of medicines for calming liver to remove endogenous,394 times of medicines for promoting blood circulation and eliminating blood stasis,370 times of medicines for invigorating Qi(气),and 359 times of medicines for dissipating wind and heat,etc.The“K-cluster analysis”of high-frequency medicines obtained two groups of medicines,namely Group 1:Sangye,Duzhong Ye,Tianma,Heye,Jiaogulan,Luobuma Ye,Yinxing Ye,Chishao,and Danshen,and Group 2:Baizhu(Atractylodes Macrocephala),Fuling(Poria),Banxia(Rhizoma Pinelliae),Huangl
出处
《中医临床研究》
2022年第28期29-32,共4页
Clinical Journal Of Chinese Medicine
基金
河南中医药大学专业学位研究生教学案例(库)建设项目(YJSALK-2020-09)。
关键词
聚类分析
眩晕
高血压病
处方
Cluster analysis
Vertigo
Hypertension
Prescription
