摘要
目的探索肝切除手术切缘距离对肝内胆管癌患者的影响。方法选取2018年8月—2019年8月在平度市人民医院治疗的94例肝内胆管癌患者作为研究对象,采用数字分组方式,分为短距离组和长距离组,各47例。短距离组切缘距离1~9 mm,长距离组手术切缘为>10 mm。对比两组患者预后情况、复发时间、住院时间、手术出血量、并发症状况及满意度。结果长距离组1年和2年存活率分别为85.11%、78.72%均高于短距离组,差异有统计学意义(χ^(2)=5.595、4.039,P<0.05);长距离组复发时间长于短距离组、住院时间短于短距离组,手术出血量低于短距离组,差异有统计学意义(P<0.05);两组并发症概率比较差异无统计学意义(P>0.05);长距离组治疗满意度97.87%高于短距离组,差异有统计学意义(P<0.05)。结论肝内胆管癌症患者采用肝切除手术治疗,选择切缘距离对患者治疗结果有影响,可以改善患者远期和近期预后,避免患者肿瘤复发,提升治疗满意度,可以在医学临床推广。
Objective To explore the effect of surgical margin distance in hepatectomy on patients with intrahepatic cholangiocarcinoma.Methods A total of 94 patients with intrahepatic cholangiocarcinoma who were treated in General Surgery,Pingdu People′s Hospital from August 2018 to August 2019 were selected as the research subjects.Using digital grouping method,they were divided into short-distance group and long-distance group,with 47 cases in each group.The incision margin in the short-distance group was 1-9 mm,and the surgical margin in the longdistance group was greater than 10 mm.The prognosis,recurrence time,hospital stay,surgical blood loss,complications and satisfaction were compared between the two groups.Results The 1-year and 2-year survival rates of the long-distance group were 85.11%and 78.72%,respectively,which were higher than those of the short-distance group,and the difference was statistically significant(χ^(2)=5.595,4.039,P<0.05).The recurrence time of the longdistance group was longer than that of the short-distance group,the length of hospital stay was shorter than that of the short-distance group,and the amount of surgical blood loss was lower than that of the short-distance group,and the differences were statistically significant(P<0.05).There was no statistically significant difference in the probability of complications between the two groups(P>0.05).The treatment satisfaction of the long-distance group was 97.87%higher than that of the short-distance group,and the difference was statistically significant(P<0.05).Conclusion Patients with intrahepatic bile duct cancer are treated with hepatectomy,and the choice of resection margin distance has an impact on the treatment outcome of patients.It can improve the long-term and short-term prognosis of patients,avoid tumor recurrence,and improve treatment satisfaction,which can be promoted in clinical medicine.
作者
徐秀堂
XU Xiutang(The Second Department of General Surgery,Pingdu People′s Hospital,Qingdao,Shandong Province,266700 China)
出处
《系统医学》
2022年第18期112-115,共4页
Systems Medicine