摘要
目的探讨血府逐瘀汤联合中药烫熨治疗在肌间静脉血栓中的应用价值。方法选择2020年2月—2021年7月泰安市中医二院收治的肌间静脉血栓患者60例为研究对象。按照随机数表法分为观察组和对照组,各30例。对照组使用血府逐瘀汤内服,观察组采取血府逐瘀汤联合中药烫熨局部治疗,比较两组治疗前及治疗1周后D-二聚体、纤维蛋白原及血小板计数水平变化、治疗后两组患者仍存在的临床症状、治疗前后两组患侧肢体周径差变化、住院期间两组出血相关并发症和临床效果。结果治疗后观察组血小板计数、D-二聚体、纤维蛋白原及分别为(188.5±15.9)×109/L、(0.17±0.01)mg/L、(3.1±0.1)g/L均低于对照组,差异有统计学意义(t=26.230、26.944、29.394,P<0.05)。治疗后观察组仍存在患肢粗肿、患肢胀痛和患肢体征(皮色、皮温、弹性)改变的比例分别为2例(6.7%),1例(3.3%),3例(10.0%),低于对照组的11例(36.7%),8例(26.7%)和12例(40.0%),差异有统计学意义(χ^(2)=7.954、4.706、7.200,P<0.05)。观察组治疗前后患侧肢体周径减少(3.7±0.3)cm,减少比例大于对照组的(1.5±0.4)cm,差异有统计学意义(P<0.05)。观察组发生皮下瘀斑或紫癜、大便潜血阳性、尿红细胞阳性和鼻出血等出血相关并发症的总比例为1例(3.3%)低于对照组的14(46.7%),差异有统计学意义(χ^(2)=15.022,P<0.001)。观察组治愈率(80.0%)显著高于对照组(50.0%),差异有统计学意义(χ^(2)=5.934,P<0.05)。结论针对下肢肌间静脉血栓形成者使用血府逐瘀汤联合中药熨烫局部治疗,改善高凝状态,缓解临床症状,且并发症少,临床效果可靠。
Objective To explore the application value of Xuefu Zhuyu Decoction combined with traditional Chinese medicine ironing in the treatment of intramuscular venous thrombosis.Methods A total of 60 patients with intramuscular venous thrombosis who were admitted to Tai′an Second Hospital of Traditional Chinese Medicine from February 2020 to July 2021 were selected as the research subjects.According to the random number table method,they were divided into observation group and control group,each with 30 cases.The control group was given Xuefu Zhuyu Decoction orally,while the observation group was treated with Xuefu Zhuyu Decoction combined with traditional Chinese medicine ironing.The changes of D-dimer,fibrinogen and platelet counts before treatment and 1 week after treatment,the clinical symptoms still existed after treatment,the changes of limb circumference difference before and after treatment,bleeding related complications and clinical effects of the two groups during hospitalization were compared.Results After treatment,platelets,fibrinogen and the counts of D-dimer in the observation group were(188.5±15.9)×109/L,(0.17±0.01)mg/L,(3.1±0.1)g/L lower than the control group,the difference was statistically significant(t=26.230,26.944,29.394,P<0.05).After treatment,the observation group still had swelling of the affected limb,swelling and pain of the affected limb and signs of the affected limb(skin color,skin temperature,elasticity),the proportions of changes were 2 cases(6.7%),1 case(3.3%),3 cases(10.0%)lower than that of the control group in 11 cases(36.7%),8 cases(26.7%)and 12 cases(40.0%),the difference was statistically significant(χ^(2)=7.954,4.706,7.200,P<0.05).The circumference of the affected limb in the observation group decreased by(3.7±0.3)cm before and after treatment,and the reduction ratio was greater than that in the control group(1.5±0.4)cm,the difference was statistically significant.The total proportion of bleeding-related complications such as subcutaneous ecchymosis or purpura,positive f
作者
宋彬
井海珍
郝欣
SONG Bin;JING Haizhen;HAO Xin(Department of Geriatrics,Tai′an Second Hospital of Traditional Chinese Medicine,Tai′an,Shandong Province,271000 China;Department of Ophthalmology,Tai′an Second Hospital of Traditional Chinese Medicine,Tai′an,Shandong Province,271000 China)
出处
《系统医学》
2022年第18期46-49,77,共5页
Systems Medicine
关键词
中药烫熨
肌间静脉血栓
血府逐瘀汤
高凝状态
下肢肿胀
Traditional Chinese medicine ironing
Intermuscular venous thrombosis
Xuefu Zhuyu Decoction
Hypercoagulable state
Lower extremity swelling
