摘要
目的 探析康妇炎胶囊联合左氧氟沙星胶囊治疗慢性盆腔炎的临床价值及安全性。方法 采用随机数字表法将本院收治的82例慢性盆腔炎患者分为对照组(41例,左氧氟沙星胶囊)和治疗组(41例,左氧氟沙星胶囊+康妇炎胶囊)。比较两组的治疗效果。结果 治疗后,治疗组的血浆黏度、全血低切黏度、全血高切黏度及子宫动脉搏动指数(PI)、阻力指数(RI)低于对照组,子宫动脉收缩期峰值流速(PSV)高于对照组(P<0.05)。治疗后,治疗组的血清白细胞介素-2(IL-2)水平高于对照组,C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)水平低于对照组(P<0.05)。两组的不良反应总发生率无显著差异(P>0.05)。结论 康妇炎胶囊联合左氧氟沙星胶囊可显著改善慢性盆腔炎患者的血液流变学、血液动力学,减轻炎症反应,安全性高。
Objective To explore the clinical value and safety of Kangfuyan capsule combined with levofloxacin capsule in the treatment of chronic pelvic inflammatory disease. Methods Eighty-two patients with chronic pelvic inflammatory disease treated in our hospital were divided into control group(41 cases, levofloxacin capsule) and treatment group(41 cases,levofloxacin capsule + Kangfuyan capsule) according to random number table method. The therapeutic effects of the two groups were compared. Results After treatment, the plasma viscosity, whole blood low shear viscosity, whole blood high shear viscosity, pulsation index(PI) and resistance index(RI) of uterine artery in the treatment group were lower than those in the control group, and the peak systolic velocity(PSV) of uterine artery was higher than that in the control group(P<0.05).After treatment, the level of serum interleukin-2(IL-2) in the treatment group was higher than that in the control group,while the levels of C-reactive protein(CRP) and tumor necrosis factor-α(TNF-α) were lower than those in the control group(P <0.05). There was no significant difference in the total incidence of adverse reactions between the two groups(P >0.05).Conclusion Kangfuyan capsule combined with levofloxacin capsule can significantly improve the hemorheology and hemodynamics of patients with chronic pelvic inflammatory disease, and reduce the inflammatory reaction, with high safety.
作者
张爽
ZHANG Shuang(the Fourth People's Hospital of Zhumadian,Zhumadian 463000,China)
出处
《临床医学研究与实践》
2022年第30期125-127,共3页
Clinical Research and Practice
关键词
康妇炎胶囊
左氧氟沙星胶囊
慢性盆腔炎
Kangfuyan capsule
levofloxacin capsule
chronic pelvic inflammatory disease
