摘要
目的行子宫内膜息肉(EPs)摘除术患者生育能力易受到影响。文中探讨35岁及以下患者EPs摘除术后复发因素。方法回顾性分析2016年1月至2017年12月江苏省中医院妇科收治的117例经病理证实的35岁及以下EPs患者临床资料。经筛选纳入113例作为研究对象,并根据患者术后是否复发分为复发组(n=20)及未复发组(n=93),对比两组一般临床资料,分析影响35岁及以下EPs患者术后复发的独立危险因素。结果Logistic回归分析发现,息肉多发(OR=2.008,95%CI=1.081~3.730)、术后未使用孕激素治疗(OR=1.931,95%CI=1.054~3.538)是影响35岁及以下EPs术后复发的独立危险因素。上述因素在35岁及以下EPs术后复发中的预测敏感度85.46%、特异度为76.39%,AUC为0.731。结论EPs摘除术后具有较高的复发率,息肉多发、术后未使用孕激素治疗是影响35岁及以下EPs患者术后复发的独立危险因素;且将上述因素建立Logistic模型对于术后复发风险预测效能较佳,可为临床早期干预提供客观依据。
Objective To investigate the recurrence factors in patients under 35 years old after endometrial polypectomy.Methods This study retrospectively analyzed the general clinical data of 117 patients under 35 years old who had pathologically confirmed endometrial polyps(EPs)and were admitted to the Department of Gynecology,Jiangsu Provincial Hospital of Traditional Chinese Medicine from January 2016 to December 2017.According to the inclusion and exclusion criteria,113 patients were finally selected as the research subjects.The patients were divided into recurrence group(n=20)and non-recurrence group(n=93)according to the status of postoperative recurrence.The general clinical data of the two groups were compared to screen the independent risk factors for postoperative recurrence of EPs in patients under 35 years old.Results Logistic regression analysis found that multiple polyps,and no use of progestins after operation were independent risk factors for postoperative recurrence of EPs in patients under 35 years old.The sensitivity,specificity and AUC of the prediction model constructed based on these risk factors to predict postoperative recurrence of EPs in patients under 35 years old were 85.46%,76.39%and 0.731,respectively.Conclusion The recurrence rate of EPs is high after operation.Multiple polyps,PCOS,and no use of progestins after operation are independent risk factors for postoperative recurrence of EPs in patients under 35 years old.The prediction model constructed based on these risk factors has good predictive performance,which can provide an objective basis for early clinical intervention.
作者
林凯璇
郭红玉
张秦
LIN Kai-xuan;GUO Hong-yu;ZHANG Qin(Department of Gynecology,Jiangsu Province Hospital Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210008,Jiangsu,China)
出处
《医学研究生学报》
CAS
北大核心
2022年第10期1051-1054,共4页
Journal of Medical Postgraduates
基金
国家自然科学基金(82074478)。
关键词
子宫内膜息肉
复发
危险因素
预测
endometrial polyps
recurrence
risk factor
prediction
