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急性缺血性脑卒中患者短期预后不良情况及影响因素的分析研究 被引量:2

Analysis on the short-term poor prognosis and its influencing factors in patients with acute ischemic stroke
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摘要 目的探讨急性缺血性脑卒中患者短期预后不良情况及其影响因素,为其预后改善措施的制定提供参考。方法选取2020年12月至2022年3月在该院住院的急性缺血性脑卒中患者,将其根据预后情况(起病第21天改良Rankin量表评分)分为预后好(≤2分)组和预后差(≥3分)组。比较两组的临床资料数据,并采用多因素logistics回归分析患者短期预后的影响因素。结果最终共纳入患者61例,其中预后好组35例,预后差组26例。单因素分析显示有并发症(P=0.029)、入院时美国国立卫生院卒中量表(NIHSS)评分高(P<0.001)、尿素氮高(P=0.015)、中性粒细胞/淋巴细胞绝对值高(P=0.022)是急性缺血性脑卒中患者短期预后不良的影响因素。多因素logistics回归分析表明:入院时NIHSS评分高是急性缺血性脑卒中患者短期预后的独立危险因素(P=0.003)。结论入院时NIHSS评分高是急性缺血性脑卒中患者短期预后不良的预后因素,应加强注意。 Objective To investigate the short-term poor prognosis and its influencing factors of patients with acute ischemic stroke,in order to provide reference for the formulation of measures to improve the prognosis.Methods The patients with acute ischemic stroke who were hospitalized in the hospital from December 2020 to March 2022 were selected,and they were divided into the good prognosis(≤2 points)group and the poor prognosis(≥3 points)group according to the prognosis situation(Modified Rankin Scale score on the 21 st day of onset).Then the clinical data of the two groups were compared,and the influencing factors of short-term prognosis of patients were analyzed by multivariate logistic regression analysis.Results A total of 61 patients were finally included,including 35 in the good prognosis group and 26 in the poor prognosis group.The univariate analysis showed that complications(P=0.029),high National Institutes of Health Stroke Scale(NIHSS)score at admission(P<0.001),high urea nitrogen(P=0.015),and high absolute value of neutrophil/lymphocyte(P=0.022)were the influencing factors for the short-term poor prognosis in patients with acute ischemic stroke.Multivariate logistic regression analysis showed that high NIHSS score at admission was an independent risk factor for short-term prognosis in patients with acute ischemic stroke(P=0.003).Conclusion A high NIHSS score at admission is a prognostic factor for short-term poor prognosis in patients with acute ischemic stroke,which should be paid more attention to.
作者 崔燕玲 郑剑华 曹莹 戴建武 CUI Yanling;ZHENG Jianhua;CAO Ying;DAI Jianwu(Department of Neurology,Guangzhou Twelfth People’s Hospital,Guangzhou,Guangdong 510620,China)
出处 《现代医药卫生》 2022年第20期3460-3464,共5页 Journal of Modern Medicine & Health
关键词 缺血性脑卒中 急重症 预后 NIHSS评分 影响因素 Acute ischemic stroke Acute and severe disease Prognosis NIHSS score Influencing factor
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