摘要
目的:探讨上海市60岁以上高血压患者动脉粥样硬化性心血管病(ASCVD)危险分层及血脂达标情况,和ASCVD高危患者LDL-C水平未达标的影响因素。方法:13735例60岁以上无ASCVD病史的体检者被分为非高血压组(7125例)与高血压组(6610例),比较两组一般资料。依据ASCVD危险分层评估,3925例LDL-C水平未达标的高血压患者被分为ASCVD低危组(554例)、中危组(42例)与高危组(3329例),比较各组间血脂水平。依据LDL-C水平是否达标,分析高血压ASCVD高危患者LDL-C水平未达标的影响因素。结果:与非高血压组比较,高血压组女性、吸烟、慢性肾脏病(CKD)比例,年龄、腰围、BMI、SBP、DBP、FBG、TC、TG水平均显著升高,农村人员、合并DM比例均显著降低(P均=0.001)。与ASCVD低危组比较,ASCVD中危组、高危组TC、LDL-C、HDL-C水平均显著降低;与ASCVD中危组比较,ASCVD高危组上述血脂水平均显著升高(P<0.05或<0.01)。多因素Logistic回归分析显示,女性、农村人员、吸烟是ASCVD高危患者LDL-C水平未达标的独立危险因素(OR=2.169~3.643,P均=0.001),高龄、合并DM、合并CKD是其独立保护因素(OR=0.192~0.728,P<0.05或<0.01)。结论:上海市60岁以上高血压ASCVD高危患者血脂达标率低、女性、农村人员、吸烟是此类患者LDL-C水平未达标的独立危险因素。
Objective:To explore risk stratification of atherosclerotic cardiovascular disease(ASCVD)and blood lipid standard-reaching condition in hypertensive(EH)patients>60 years old in Shanghai,and study influencing factors for LDL-C level not reaching standard in ASCVD high-risk patients.Methods:According to suffering from EH or not,a total of 13735 subjects>60 years old without ASCVD history were divided into non EH group(n=7125)and EH group(n=6610),and general clinical data were compared between two groups.According to ASCVD risk stratification,a total of 3925 EH patients with LDL-C level no reach standard were divided into ASCVD low risk group(n=554),intermediate risk group(n=42)and high risk group(n=3329),and levels of blood lipids were compared among all groups.According to whether LDL-C level reached standard or not,the 3653 EH patients with ASCVD high-risk were divided into SR group(n=324)and non SR group(n=3329),and general clinical data were compared between two groups.Influencing factors for LDL-C level no reach standard in EH patients with ASCVD high-risk were analyzed.Results:Compared with non EH group,there were significant rise in percentages of female,smoking and chronic kidney disease(CKD),age,waist circumference,BMI,levels of SBP,DBP,FBG,TC and TG,and significant reductions in percentages of personnel living in rural areas and DM in EH group(P=0.001 all).Compared with ASCVD low risk group,there were significant reductions in levels of TC,LDL-C and HDL-C in intermediate and high risk group;compared with intermediate risk group,there were significant rise in above blood lipid levels in high risk group(P<0.05 or<0.01).Multivariate Logistic regression analysis indicated that female,personnel living in rural areas and smoking were independent risk factors for LDL-C level not reaching standard in EH patients with ASCVD high-risk(OR=2.169~3.643,P=0.001 all),and advanced age,DM and CKD were its independent protective factors(OR=0.192~0.728,P<0.05 or<0.01).Conclusion:Blood lipid reaching standard rate of hyperte
作者
徐佶佶
高金丽
潘宇峰
黄全
李振华
张俊峰
范虞琪
XU Ji-ji;GAO Jin-li;PAN Yu-feng;HUANG Quan;LI Zhen-hua;ZHANG Jun-feng;FAN Yu-qi(Department of Cardiology,Ninth Affiliated People's Hospital of School of Medicine,Shanghai Jiaotong University,Shanghai,200011,China)
出处
《心血管康复医学杂志》
CAS
2022年第5期542-546,共5页
Chinese Journal of Cardiovascular Rehabilitation Medicine
基金
上海市宝山区科学技术委员会科技创新项目(19-E-15)
上海市中西医学会社区医学与健康管理研究项目(2021-49)。
