摘要
目的对比观察经桡动脉与经股动脉行经导管动脉化疗栓塞术(transcatheter arterial chemoembolization,TACE)治疗原发性肝癌(primary hepatic carcinoma,PHC)的效果及安全性。方法回顾性分析2015年6月~2021年10月于哈尔滨医科大学附属第四医院3426例接受TACE治疗的PHC患者,其中1242例经桡动脉穿刺(A组),2184例经股动脉穿刺(B组),对比研究两组的穿刺、手术成功率及手术时间和曝光时间等相关指标。结果A组穿刺成功率99.52%(1236/1242),手术成功率99.11%(1231/1242);B组穿刺成功率100%(2184/2184),手术成功率99.86%(2181/2184)。两组穿刺成功率及手术成功率差异均无统计学意义(P均>0.05)。B组术后并发症发生率为8.75%(191/2184),高于A组的5.31%(66/1242)(P=0.01)。A组穿刺时间长于B组(P<0.05),两组手术时间、曝光时间及曝光剂量差异均无统计学意义(P均>0.05)。结论经桡动脉行TACE治疗PHC与经股动脉行TACE效果相当,且并发症少,但穿刺成功率略低。经桡动脉路径安全可行,患者舒适度高,可重复性强,值得推广。
Objective To compare the efficacy and safety of transradial artery and transfemoral artery for transcatheter arterial chemoembolization(TACE)treatment of primary hepatic carcinoma(PHC).Methods From June 2015 to October 2021,data of 3426 patients with PHC treated with TACE in the Fourth Affiliated Hospital of Harbin Medical University were retrospectively analyzed,including 1242 underwent transradial artery puncture(group A)and 2184 underwent transfemoral artery(group B),the puncture and operation success rate,operation time and exposure time and the relevant indicators were compared between the two groups.Results The puncture success rate and therapeutic success rate was 99.52%(1236/1242)and 99.11%(1231/1242)in group A,while in group B was 100%(2184/2184)and 99.86%(2181/2184),respectively(P both>0.05).The incidence of postoperative complications in group B was 8.75%(191/2184),higher than that in group A 5.31%(66/1242),P=0.01.The puncture time in group A was longer than in group B(P<0.05),and there was no difference in operation time,exposure time and exposure dose between the two groups(P all>0.05).Conclusion Transradial artery for TACE treatment has similar effect and less complications,but slightly lower puncture success rate than transfemoral artery for TACE treatment.It is safe and feasible,with high comfort and repeatability,which is worthy of promotion.
作者
邹常咏
侯利芳
朱乾坤
宁玮
王东旭
闫
ZOU Chang-yong;HOU Li-fang;ZHU Qian-kun;NING Wei;WANG Dong-xu;YAN Yan(Department of Interventional Radiology,The Fourth Affiliated Hospital of Harbin Medical University,Harbin 150001,China;Department of Ultrasound in Physical Examination Center,The First Affiliated Hospital of Harbin Medical University,Harbin 150001,China)
出处
《哈尔滨医科大学学报》
CAS
2022年第3期263-266,270,共5页
Journal of Harbin Medical University
基金
黑龙江省卫生计生委科研课题(2018410)
黑龙江省博士后资助课题(LBH-Z18229)
哈尔滨医科大学附属第四医院科技创新人才项目(HYDSYCXRC202117)。
关键词
肝细胞癌
股动脉
桡动脉
经导管动脉化疗栓塞术
hepatocellular carcinoma
femoral artery
radial artery
transcatheter arterial chemoembolization
