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二氧化氯在不同浓度有机干扰物条件下消毒效果的评价

Analysis of Germicidal Efficacy of Chlorine Dioxide Disinfectant under Different Organic Interfering Substances
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摘要 目的:分析在不同有机物浓度下二氧化氯消毒剂对细菌、真菌、细菌芽孢的杀灭效果。方法:依据GB/T38502-2020《消毒剂实验室杀菌效果检验方法》,采用悬液定量法进行了实验室观察。结果:在0.3%、3%、30%的有机干扰物浓度下,二氧化氯消毒剂对大肠杆菌、金黄色葡萄球菌、白色念珠菌、枯草杆菌黑色变种芽孢的杀灭效果有极大的差异,在30%牛血清白蛋白条件下,二氧化氯的消毒效果减弱明显,作用浓度为250 mg/L、作用时间为1 h时,对大肠杆菌、金黄色葡萄球菌的杀灭对数值>5.00;作用浓度为500 mg/L、作用时间为30 min时,对白色念珠菌的杀灭对数值>5.00;作用浓度为1250 mg/L、作用时间为1 h时,对枯草杆菌黑色变种芽孢的杀灭对数值>5.00。结论:不同有机干扰物浓度对二氧化氯的消毒效果有不同程度的影响,在进行二氧化氯消毒时需结合实际消毒对象的洁净程度调整作用浓度及作用时长以达到消毒效果。 Objective: To analyze the germicidal efficacy of chlorine dioxide on bacteria, fungi and spore under different organic interfering substance. Methods:According to GB/T 38502-2020, suspension quantitative germicidal testing methods were used to carry out laboratory observation. Results: under the concentration of 0.3 %, 3 % and 30 % BSA, the germicidal efficacy of chlorine dioxide disinfectant on Escherichia coli, Staphylococcus aureus, Candida albicans and spores of Bacillus subtilis var.niger had great differences. Under the condition of 30 % BSA, the germicidal capacity of chlorine dioxide was obviously weakened. The killing log values of Escherichia coli and Staphylococcus aureus exposed to the solution of 250 mg/L chlorine dioxide for 1 h were both greater than 5.00. The killing log value of Candida albicans exposed to the solution of 500 mg/L chlorine dioxide for 30 min was greater than 5.00. The killing log value of spores of Bacillus subtilis var.niger exposed to the solution of 1250 mg/L chlorine dioxide for 1 h was greater than 5.00. Conclusion: There are different degrees of influences on the germicidal efficacy of chlorine dioxide under different organic interfering situations. The concentration and duration of disinfection should be adjusted according to the actual object in order to achieve disinfection effect.
作者 周颖璇 朱文信 杜柳珊 Zhou Yingxuan;Zhu Wenxin;Du Liushan(Guangzhou Quality Supervision and Testing Institute,Guangzhou 511447,China)
出处 《广东化工》 CAS 2022年第20期200-202,共3页 Guangdong Chemical Industry
关键词 二氧化氯 有机干扰物 中和剂 杀菌效果 杀灭对数值 影响因素 chlorine dioxide organic interfering substance neutralizer germicidal efficacy killing log value influence factors
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