摘要
目的探索实验猪不同脊髓轴向张力条件下脊髓周围血流的变化。方法采用3头雄性广西白猪进行造模,应用术中超声测量猪脊髓原始状态、腰椎间隙L撑开5 mm状态、腰椎间隙L短缩5 mm状态下脊髓横断面和矢状面的直径及脊髓M波振幅、脊髓周围血流的时间-强度曲线数据,并采用配对t检验进行数据比较。结果与猪脊髓原始状态相比,在撑开状态下猪脊髓直径变小、脊髓搏动幅度降低、脊髓周围血流减慢、血流曲线上升幅度减缓、血流灌注量减少,差异均有统计学意义(P均<0.05)。在短缩状态下猪脊髓直径变大,搏动幅度增加,脊髓周围血流曲线上升幅度减缓,血流灌注量减少,与猪脊髓原始状态相比差异均有统计学意义(P均<0.05)。结论猪脊髓张力变化与脊髓的搏动振幅和周围血流灌注量相关。
Objective To explore the changes of bloodstream around spinal cord under different axial spinal cord tensions in experimental pigs.Methods Three male Guangxi white pigs were used for modeling.Intraoperative ultrasound was used to measure the diameter of spinal cord cross section and sagittal plane,spinal cord M-wave amplitude and timeintensity curve of bloodstream around spinal cord in porcine spinal cord original state,lumbar intervertebral space L3/4distraction 5 mm state and lumbar intervertebral space L3/4 shortening 5 mm state,and the data were compared by paired t test.Results Compared with those in the original state of porcine spinal cord,in the distraction state the porcine spinal cord diameter was significantly smaller,the pulsation amplitude was significantly decreased,the perispinal bloodstream was significantly slower,the rising amplitude was significantly decelerated,and the blood perfusion was significantly decreased(all P<0.05).Compared with the original state,in the shortening state the diameter of the spinal cord was significantly larger,the pulsation amplitude was significantly increased,the rising amplitude of bloodstream curve around the spinal cord was significantly slower,and the blood perfusion was significantly decreased(all P<0.05).Conclusion The changes of porcine spinal cord tension are related to the pulsatile amplitude of spinal cord and perispinal blood perfusion.
作者
林峰
季承龙
孙凯强
王元
徐锡明
史建刚
LIN Feng;JI Cheng-long;SUN Kai-qiang;WANG Yuan;XU Xi-ming;SHI Jian-gang(Department of Orthopaedics,The Second Affiliated Hospital of Naval Medical University(Second Military Medical University),Shanghai 200003,China;Department of Orthopaedics,The Affiliated Yantai Yuhuangding Hospital of Qingdao University,Yantai 264000,Shandong,China)
出处
《海军军医大学学报》
CAS
CSCD
北大核心
2022年第9期1096-1101,共6页
Academic Journal of Naval Medical University
关键词
脊髓张力
弓弦病
超声造影
脊髓周围血流
spinal cord tension
bowstring disease
contrast-enhanced ultrasonography
perispinal bloodstream
