摘要
骨关节炎(osteoarthritis,OA)是一种以关节软骨退行性改变和继发性骨增生为特征的慢性关节疾病,其中以膝关节骨关节炎(knee osteoarthritis,KOA)最为常见。目前针对KOA的非手术治疗仅能达到缓解疼痛、改善功能的目的。积极的手术治疗效果虽好,但假体定位困难,手术难度高,因此急需新的治疗方式以改善患者预后。基于KOA的最新临床研究,本文对膝神经射频消融术、机器人辅助膝关节置换术、生物治疗和激光治疗等4种新的治疗方式开展评述。
Osteoarthritis(OA)is a chronic joint disease characterized by progressive cartilage degradation and subchondral bone remodeling,of which knee osteoarthritis(KOA)is the most common.Current non-surgical treatment for KOA aims to alleviate pain and improve function.Although the effect of knee arthroplasty is good,the operation is complex and accompanied by problems such as difficult implant positioning.There is an urgent need for new treatments to improve the prognosis of patients.Based on the latest clinical research of KOA in recent two years,this paper summarizes 4 kinds of new treatment methods including genicular nerve radiofrequency ablation,robot-assisted knee arthroplasty,regenerative medicine and laser therapy.
作者
王琦
易诚青
WANG Qi;YI Cheng-qing(Department of Orthopedics,Shanghai Pudong Hospital-Fudan University Pudong Medical Center,Shanghai 201399,China)
出处
《复旦学报（医学版）》
CAS
CSCD
北大核心
2022年第5期765-770,共6页
Fudan University Journal of Medical Sciences
基金
上海市浦东新区卫健委临床高原学科项目(PWYgy2021-04)
上海市浦东新区卫健委联合攻关项目(PW2021D-08)。
