摘要
目的利用2012—2018年洛阳市肿瘤登记数据评估全市女性乳腺癌的流行情况,为全市乳腺癌的防控提供依据。方法利用2012—2018年肿瘤登记数据分城乡地区和年龄组评估全市女性乳腺癌的流行情况,计算发病率、死亡率、累积率、截缩率、标化率和平均年度变化百分比(average annual percentage change,AAPC)等指标,人口标准化率按照2000年中国标准人口结构(简称中标率)和Segi's世界标准人口结构(简称世标率)进行计算。结果2012—2018年洛阳市女性乳腺癌发病人数6600例,平均发病率为41.43/10万,中国人口和世界人口标化发病率分别为33.01/10万和30.87/10万,0~74岁累积发病率为3.35%,35~64岁截缩率为74.71/10万。乳腺癌位居女性全部恶性肿瘤发病的第一位(15.80%)。2012—2018年洛阳市女性乳腺癌死亡人数1491例,死亡率为8.88/10万,中国人口和世界人口标化死亡率分别为6.58/10万和6.32/10万,0~74岁累积死亡率为0.73%,35~64岁截缩率为13.26/10万,乳腺癌死亡位居女性全部恶性肿瘤死亡的第五位(6.99%)。洛阳市女性乳腺癌发病和死亡年龄集中在40~69岁和40~79岁人群。城市地区发病和死亡(中标率:40.03/10万,8.59/10万)均高于农村地区(中标率:29.87/10万,5.69/10万)。洛阳市女性乳癌世界标化发病率随时间呈上升趋势(AAPC为3.102%,95%CI为0.487%~5.813%,P<0.05),世界标化死亡率无明显变化(AAPC为-6.681%,95%CI为-13.501%~0.746%,P>0.05)。结论乳腺癌是威胁洛阳市女性健康的主要恶性肿瘤之一,疾病负担日益加重,应进一步加强乳腺癌的综合防治工作。
Objective To estimate the incidence of female breast cancer in Luoyang City during 2012-2018 based on the data from local cancer registries,and to provide a basis for breast cancer prevention and control in this city.Methods The cancer registration data from 2012 to 2018 were used to evaluate the prevalence of female breast cancer in urban and rural areas as well as age groups in Luoyang City.The incidence rate,mortality rate,cumulative rate,truncation rate,standardized rate and average annual percentage change(AAPC)were calculated.China’s 2000 census population and Segi’s population were used to calculate the age-standardized rate.Results A total of 6,600 female breast cancer cases were reported in Luoyang City during 2012-2018,with the average incidence rate of 41.43/100,000.The age-standardized incidence rate by Chinese standard population(ASIRC)and by world standard population(ASIRW)was 33.01/100,000 and 30.87/100,000,respectively.The cumulative incidence rate in the age group of 0-74 years was 3.35%,and the truncated rate in the age group of 35-64 years 74.71/100,000.Breast cancer ranked first among the incidence of all malignant tumors in women(15.80%).There were 1,491 female deaths due to breast cancer in Luoyang City during 2012-2018,with the mortality rate being 8.88/100,000.The age-standardized mortality rate by Chinese standard population(ASMRC)and by world standard population(ASMRW)were 6.58/100,000 and 6.32/100,000,respectively.The cumulative mortality rate in the age group of 0-74 years was 0.73%,and the truncated rate in the age group of 35-64 years 13.26/100,000.Breast cancer deaths ranked the fifth among all female deaths owing to malignant tumors(6.99%).Most of the female breast cancer cases in Luoyang City were women aged 40-69 years,and most of the female deaths due to breast cancer were women aged 40-79 years.The cancer incidence and mortality in urban areas(ASIRC:40.03/100,000,ASMRC:8.59/100,000)were higher than those in rural areas(ASIRC:29.87/100,000,ASMRC:5.69/100,000).ASIRW of female
作者
闫云燕
常颖
秦延锦
YAN Yun-yan;CHANG Ying;QIN Yan-jin(Luoyang Municipal Center for Disease Control and Prevention,Luoyang,Henan 471000,China;Yanshi District Center for Disease Control and Prevention,Yanshi,Henan 471900,China)
出处
《实用预防医学》
CAS
2022年第10期1210-1214,共5页
Practical Preventive Medicine
关键词
发病率
死亡率
乳腺癌
平均年度变化百分比
incidence rate
mortality rate
breast cancer
average annual percentage change
