摘要
目的:挖掘分析冠状动脉粥样硬化性心脏病(冠心病)中医病案的证候与用药规律。方法:运用Excel及Python软件,对从国家知识基础设施数据库(CNKI)、中国学术期刊数据库(CSPD)、中文科技期刊数据库(CCD)等数据库中收集的343个冠心病临床病案的证素、证候以及用药进行频数统计、权值计算和数据可视化。结果:冠心病最常见的3个证素为血瘀、痰和气虚,最常见的3个证型为气虚血瘀、气滞血瘀和痰瘀互结,出现频率居前5位的证候为胸闷、胸痛、气短、苔白和舌暗,使用频率居前5位的中药为丹参、甘草、川芎、半夏和茯苓。结论:通过证素-证候分析得出,气虚血瘀特有的证候有苔白、舌淡、脉沉、汗出与气短,气滞血瘀特有的证候有瘀点(斑)舌与苔黄,痰瘀互结特有的证候有苔腻、纳呆、苔厚、脉滑与舌胖;通过证素-中药分析得出,气虚血瘀证用药可归纳为补阳还五汤合八珍汤加减,气滞血瘀证用药可归纳为柴胡疏肝散合桃红四物汤加减,痰瘀互结证用药可归纳为温胆汤合瓜蒌薤白白酒汤加减。
Objective:To analyze the syndromes and medication regularity from TCM clinical cases with coronary atherosclerotic heart disease(coronary heart disease).Methods:The information on syndrome elements, syndromes, and medication of 343 TCM clinical cases of coronary heart disease was collected from databases such as CNKI,Wanfang Data, and VIP for frequency analysis, weight calculation, and data visualization by Excel and Python.Results:The top 3 common syndrome elements are blood stasis, phlegm, and qi deficiency.The top 3 common syndromes are qi deficiency and blood stasis, qi stagnation and blood stasis, and combined phlegm and blood stasis.The top 5 common syndromes are chest tightness, chest pain, shortness of breath, white coating, and dark tongue.In terms of frequency of use, the top 5 Chinese medicines are Salviae Miltiorrhizae Radix et Rhizoma, Glycyrrhizae Radix et Rhizoma, Chuanxiong Rhizoma, Pinelliae Rhizoma, and Poria.Conclusion:As revealed by the analysis of syndrome elements-syndromes, white coating, pale tongue, deep pulse, sweating, and shortness of breath are characteristic symptoms for qi deficiency and blood stasis, petechia or ecchymotic tongue and yellow coating for qi stagnation and blood stasis, and greasy and thick coating, poor appetite, slippery pulse, and fat tongue for combined phlegm and blood stasis.According to the analysis of syndrome elements-Chinese medicines, Buyang Huanwu Decoction combined with Bazhen Decoction with modification is used for qi deficiency and blood stasis, Chaihu Shugan Powder combined with Taohong Siwu Decoction with modification for qi stagnation and blood stasis, and Wendan Decoction combined with Gualou Xiebai Baijiu Decoction with modification for combined phlegm and blood stasis.
作者
陈善达
梁昊
李亮
CHEN Shanda;LIANG Hao;LI Liang(Hunan University of Chinese Medicine,Changsha 410208,China;Provincial Key Laboratory of TCM Diagnostics,Hunan University of Chinese Medicine,Changsha 410208,China;Key Laboratory of TCM Heart and Lung Syndrome Differentiation&Medicated Diet and Dietotherapy,Hunan University of Chinese Medicine,Changsha 410208,China)
出处
《世界中医药》
CAS
2022年第17期2501-2505,共5页
World Chinese Medicine
基金
湖南省自然科学基金项目(2019JJ40214)
湖南省中医药科研计划项目重点项目(202004)
湖南省教育厅重点项目(19A380)
湖南省研究生科研创新项目(CX2018B465)。
关键词
冠心病
中医
Python软件
数据挖掘
证素辨证
证候
Coronary heart disease
Traditional Chinese medicine
Python
Data mining
Syndrome element differentiation
Syndrome
