摘要
砷和砷的化合物被列为有毒有害的环境污染物之一,饮水、食用海产品、使用化妆品和吸入烟草烟雾等是人类砷暴露的主要途径。砷对妊娠结局的不良影响备受关注,研究表明,孕产妇产前暴露于高水平砷可使自然流产的发生风险增加。本文收集1992—2020年国内外砷暴露与自然流产关联的流行病学研究文献,对砷暴露与自然流产的关联进行综述,并探讨砷暴露导致自然流产的机制,为自然流产的早期预防提供依据。
Arsenic and arsenic compounds have been listed as one of the toxic and harmful environment pollutants,and drinking,seafood intake,use of skincare products and inhalation of tobacco smoke are main routes of exposure to human arsenic exposure.The adverse effects of arsenic on pregnant outcomes have been paid much attention.Prenatal exposure to high-level arsenic has been found to increase the risk of spontaneous abortion among pregnant women.Based on national and international epidemiological studies on the correlation between arsenic exposure and spontaneous abortion during the period between 1992 and 2020,we review the association between arsenic exposure and spontaneous abortion and describe the mechanisms underlying spontaneous abortion caused by arsenic exposure,so as to provide insights into early prevention of spontaneous abortion.
作者
裴航
马执彬
廖继芸
杨晨(综述)
刘兴荣(审校)
PEI Hang;MA Zhibin;LIAO Jiyun;YANG Chen;LIU Xingrong(School of Medicine,Lanzhou University,Lanzhou,Gansu 730000,China)
出处
《预防医学》
2022年第10期1011-1014,1019,共5页
CHINA PREVENTIVE MEDICINE JOURNAL
基金
甘肃省社科规划重点招标课题(20ZD017)
兰州大学“一带一路”专项经费资助项目(2018年)。
关键词
砷
自然流产
妊娠结局
arsenic
spontaneous abortion
pregnancy outcome
