摘要
Toll样受体9(Toll-like receptor 9,TLR9)是免疫系统中的重要受体,可以介导固有免疫及适应性免疫,且在其中具有桥梁作用,近年来TLR9在肿瘤免疫中的研究逐渐深入,发现其在食管癌、胃癌等多种感染相关上消化道肿瘤的发生发展中具有重要的作用。本文对近年相关研究进行综述,旨在探讨TLR9在上消化道肿瘤中未来的研究及临床价值。
TLR9 is an important receptor in the immune system,which can mediate innate immunity and adaptive immunity,and plays a bridge role in it.In recent years.TLR9 has been intensively studied in tumor immunity,and found that it plays an important role in the occurrence and development of various infection-related upper gastrointestinal tumors such as esophageal cancer and gastric cancer.This article reviews the related research in recent years to explore the future research and clinical value of TLR9 in upper gastrointestinal tumors.
作者
张志博
ZHANG Zhi-bo(First Affiliated Hospital,and College of Clinical Medicine of Henan University of Science and Technology,Luoyang,China,471003)
出处
《食管疾病》
2022年第3期188-192,共5页
Journal of Esophageal Diseases
关键词
TOLL样受体9
感染相关肿瘤
食管癌
胃癌
炎症
Toll-like receptor 9
infection-related tumors
esophageal cancer
gastric cancer
inflammation
