摘要
目的对2型糖尿病患者幽门螺旋杆菌感染情况及胃肠病变特点进行探究分析。方法选取2020年1月—2022年1月于莆田涵江医院接受胃镜检查的患者144例,72例2型糖尿病患者纳入观察组,72例非2型糖尿病患者纳入对照组,对两组幽门螺旋杆菌感染情况、胃肠病变情况进行分析。结果观察组幽门螺旋杆菌感染发生率61.11%,高于对照组16.67%,消化性溃疡、反流性溃疡、胃肠息肉检出率38.88%、13.89%、11.11%,高于对照组13.89%、2.78%、2.78%,差异有统计学意义(P<0.05);观察组中合并幽门螺旋杆菌感染患者消化性溃疡22例、十二指肠球炎6例、反流性食管炎8例,多于未合并幽门螺旋杆菌感染患者;观察组消化性溃疡病灶直径≥1.0 cm占比78.57%,高于对照组20.00%,差异有统计学意义(χ^(2)=8.492,P<0.05);观察组中消化性溃疡病灶直径≥1.0 cm患者中90.91%合并幽门螺旋杆菌感染;观察组糜烂性胃炎检出率高于对照组,非萎缩性胃炎检出率低于对照组,差异有统计学意义(χ^(2)=4.255、7.107,P<0.05)。结论相对于一般人群而言,2型糖尿病患者幽门螺旋杆菌感染率更高,胃肠病变明显,且合并幽门螺旋杆菌感染2型糖尿病患者胃肠病变严重程度更高,临床应给予高度重视。
Objective To explore the characteristics of Helicobacter pylori infection and gastrointestinal lesions in patients with type 2 diabetes mellitus.Methods A total of 144 patients who underwent gastroscopy in Putian Hanjiang Hospital from January 2020 to January 2022 were selected,72 patients with type 2 diabetes were included in the observation group,and 72 patients without type 2 diabetes were included in the control group.The situation and gastrointestinal lesions were analyzed.Results The incidence of Helicobacter pylori infection in the observation group was61.11%,which was 16.67% higher than that in the control group The detection rates of peptic ulcer,reflux ulcer and gastrointestinal polyps of the observation group were 38.88%,13.89% and 11.11%,which were higher than 13.89%,2.78% and 2.78% of the control group,the difference was statistically significant(P<0.05);in the observation group,there were 22 cases of peptic ulcer,6 cases of duodenitis,and 8 cases of reflux esophagitis in patients with Helicobacter pylori infection,more than the patients without Helicobacter pylori infection;78.57% of the observation group had peptic ulcer lesions with a diameter of≥1.0 cm,which was 20.00% higher than that of the control group,and the difference was statistically significant(χ^(2)=8.492,P<0.05);90.91% of the patients with ulcer lesion diameter≥1.0 cm were associated with Helicobacter pylori infection;the detection rate of erosive gastritis in the observation group was higher than that in the control group,and the detection rate of non-atrophic gastritis was lower than that in the control group,the difference was statistically significant(χ^(2)=4.255,7.107,P<0.05).Conclusion Compared with the general population,patients with type 2 diabetes have a higher infection rate of Helicobacter pylori and obvious gastrointestinal lesions.In addition,the severity of gastrointestinal lesions in patients with type 2 diabetes mellitus with Helicobacter pylori infection is higher,and clinical attention should be paid to it.
作者
王腾
高新钟
苏志峰
WANG Teng;GAO Xinzhong;SU Zhifeng(Department of Gastroenterology,Putian Hanjiang Hospital,Putian,Fujian Province,351111 China)
出处
《糖尿病新世界》
2022年第15期68-71,79,共5页
Diabetes New World Magazine
关键词
2型糖尿病
幽门螺旋杆菌
胃肠病变
感染
Type 2 diabetes
Helicobacter pylori
Gastrointestinal lesions
Infection
