摘要
随着恶性肿瘤精准化诊疗理念的不断深入,在从微观视角探索肿瘤发生发展的过程中涌现了许多对临床决策有价值的信息载体,循环肿瘤DNA(circulating tumor DNA,ctDNA)就是其中之一。在肿瘤发展的不同阶段,ctDNA展现出了包括评估疗效、预测预后、监测复发等在内的多种诊疗价值。本文主要阐述ctDNA在非小细胞肺癌临床诊疗不同时期的应用研究进展。
With the concept of"Precision Medicine"in malignant tumors popularized,many substances carrying valuable clinical information have emerged in the process of exploring the occurrence and development of tumors from a microscopic perspective.Circulating tumor DNA(ctDNA)is one of them.In various clinical stages of cancer,ctDNA exhibits rich diagnostic values including demonstrating the efficacy of treatment,predicting prognosis,and monitoring disease recurrence.This article mainly describes the application and research progress of ctDNA in different stages of clinical diagnosis and treatment of non-small cell lung cancer.
作者
雷思雨
王燕
Siyu LEI;Yan WANG(Department of Medical Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China)
出处
《中国肺癌杂志》
CAS
CSCD
北大核心
2022年第9期665-670,共6页
Chinese Journal of Lung Cancer
关键词
肺肿瘤
循环肿瘤DNA
研究进展
Lung neoplasms
Circulating tumor DNA
Research progress
