摘要
目的:探究牙槽骨缺损类型与引导骨再生(GBR)术后效果的关系分析。方法:回顾性选取2019年10月至2021年10月东莞市人民医院口腔科收治的行上颌前牙区种植体植入并同期GBR的患者82例为研究对象。种植后患者均采用锥形束CT(CBCT)测量植骨吸收率。并根据患者CBCT数据进行骨缺损三维结构重建,以Pearson相关性骨缺损形态学变量与植骨吸收率之间的关系,同时以ROC曲线分析始骨缺损形态学变量对植骨吸收率的预测价值。结果:GBR术后6个月,82例患者吸收率平均为(46.8±10.52)%。经CBCT对初始骨缺损进行重建后,计算显示mMD为(5.39±1.58)mm、mCA为(5.24±1.08)mm、mBL为(5.06±1.25)mm、rmCA/mMD为(1.03±0.29)、rmCA/mBL为(1.07±0.27)、rmBL/mMD为(1.00±0.33)。Pearson相关性分析显示,mCA、mBL与植骨吸收率呈负相关(r=-0.408、-0.496,P<0.05);rmCA/mMD、rmCA/mBL与植骨吸收率呈正相关(r=0.636、0.418,P<0.05)。单因素及多因素结果显示,mBL、rmCA/mMD为植骨吸收率的影响因素(P<0.05)。另ROC曲线显示,mBL、rmCA/mMD预测植骨吸收率≥45.1%的AUC分别为0.836、0.812,95%CI分别为0.743~0.921、0.722~0.902。结论:初始骨缺损形态与GBR术后的植骨效果关系密切,骨缺损形态学特征变量预测术后植骨吸收率价值较好。
Objective:To explore the relationship between the type of alveolar bone defect and the postoperative effect of guided bone regeneration(GBR).Methods:A total of 82 patients who received implants in the maxillary anterior region and underwent GBR during the same period from October 2019 to October 2021 in the Department of Stomatology of Dongguan People's Hospital were retrospectively selected as the research subjects.The bone graft resorption rate was measured by cone beam CT(CBCT)in all patients after implantation.The three-dimensional structure reconstruction of bone defect was carried out according to the patient's CBCT data,the relationship between Pearson-related bone defect morphological variables and bone graft resorption rate,and the ROC curve was used to analyze the predictive value of primary bone defect morphological variables on bone graft resorption rate.Results:Six months after GBR,the average absorption rate of 82 patients was(46.8±10.52)%.After reconstruction of the initial bone defect by CBCT,the calculation showed that the mMD was(5.39±1.58)mm,the mCA was(5.24±1.08)mm,the mBL was(5.06±1.25)mm,the rmCA/mMD was(1.03±0.29),and the rmCA was(5.06±1.25)mm./mBL was(1.07±0.27),and rmBL/mMD was(1.00±0.33).Pearson correlation analysis showed that mCA and mBL were negatively correlated with bone graft resorption rate(r=-0.408,-0.496,P<0.05);rmCA/mMD,rmCA/mBL were positively correlated with bone graft resorption rate(r=0.636,0.418,P<0.05).Univariate and multivariate results showed that mBL and rmCA/mMD were the influencing factors of bone graft resorption rate(P<0.05).In addition,the ROC curve showed that the AUCs of mBL and rmCA/mMD for predicting bone graft resorption rate≥45.1%were 0.836 and 0.812,respectively,and the 95%CIs were 0.743-0.921 and 0.722-0.902,respectively.Conclusion:The initial bone defect morphology was closely related to the effect of bone grafting after GBR,and the morphological characteristic variables of the bone defect had better value in predicting the postoperative bone gr
作者
罗焕娣
王玉玲
莫浩勋
缪小青
LUO Huandi;WANG Yuling;MO Haoxun(Dongguan People's Hospital,Guangdong Dongguan 523059,China)
出处
《河北医学》
CAS
2022年第9期1541-1545,共5页
Hebei Medicine
基金
广东省东莞市医疗卫生科技计划一般项目,(编号:2015105101207)。
关键词
牙槽骨缺损
类型
引导骨再生
植骨吸收率
锥形束CT
Alveolar bone defect
Type
Guided bone regeneration
Bone graft resorption rate
Cone beam CT
