摘要
目的探讨舒芬太尼对瑞芬太尼麻醉后早期疼痛的预防效果。方法将2021年12月—2022年2月在烟台市北海医院进行手术治疗的60例患者随机分为两组,均使用瑞芬太尼全身麻醉,应用静脉注射预防麻醉后早期疼痛,观察组使用舒芬太尼,对照组使用芬太尼,对比两组的苏醒指标、术后不同时间点视觉模拟评分法(visual analogue scale,VAS)、相关的镇静评分和不良反应。结果两组手术患者的苏醒、拔管与离开手术室时间进行比较,观察组均较对照组手术患者用时更短,差异有统计学意义(P<0.05);观察组均较对照组术后不同时间的VAS疼痛评分更低,差异有统计学意义(P<0.05);观察组术后1、2 h的Ramsay镇静评分高于对照组,差异有统计学意义(P<0.05),其余时间点均相当,差异无统计学意义(P>0.05)。观察组躁动、呛咳、嗜睡、恶心呕吐、呼吸抑制等不良反应发生率明显低于对照组,差异有统计学意义(P<0.05)。结论舒芬太尼对瑞芬太尼麻醉后早期疼痛的预防效果显著,不影响苏醒速度,明显减轻术后疼痛,不良反应发生率低,具有积极的临床意义。
Objective To investigate the preventive effect of sufentanil on early pain after remifentanil anesthesia.Methods A total of 60 patients who underwent surgical treatment in Yantai Beihai Hospital from D ecember2021 to February 2022 were randomly divided into two groups,remifentanil was used for general anesthesia and intravenous injection was used to prevent early pain after anesthesia,the observation group was given sufentanil,and the control group was given fentanyl,and the recovery indicators,visual analogue scale(VAS) at different postoperative time points,related sedation scores and adverse reactions were compared between the two groups.Results Compared the time of awakening,extubation and leaving the operating room of the two groups of patients,the observation group was shorter than the control group,and the differences were statistically significant(P <0.05).The VAS pain scores in the observation group were lower than those in the control group at different times after operation,and the differences were statistically significant(P <0.05).The Ramsay sedation score of the observation group at 1 and 2 hours after operation was higher than that of the control group,and the differences were statistically significant(P <0.05).The rest of the time points were comparable,and the difference was not statistically significant(P> 0.05).The incidences of adverse reactions such as restlessness,choking cough,lethargy,nausea and vomiting,and respiratory depression in the observation group were significantly lower than those in the control group,and the difference was statistically significant(P <0.05).Conclusion Sufentanil has a significant preventive effect on early pain after remifentanil anesthesia,does not affect the recovery speed,significantly reduces postoperative pain,and has a low incidence of adverse reactions,which has positive clinical significance.
作者
曹贻元
CAO Yiyuan(Department of Anesthesiology,Beihai Hospital of Yantai,Yantai Shandong 265701,China)
出处
《中国卫生标准管理》
2022年第15期109-113,共5页
China Health Standard Management
关键词
瑞芬太尼
麻醉
舒芬太尼
痛觉超敏
早期疼痛
预防效果
remifentanil
anesthesia
sufentanil
hypersensitivity to pain
early pain
protective effect
