摘要
目的 探讨在全身麻醉患者术中给予舒芬太尼联合瑞芬太尼的麻醉价值。方法 选取2020年6月—2021年12月期间在单县中心医院进行全身麻醉手术的180例患者,采取随机数表法将其平均分成两组,每组90例,对照组采取瑞芬太尼进行麻醉,研究组联合应用舒芬太尼与瑞芬太尼进行麻醉,对比两组麻醉及预后效果。结果 研究组患者收缩压(132.12±12.33)mmHg、舒张压(78.14±8.61)mmHg、心率(74.34±7.49)次/min波动幅度小于对照组,差异有统计学意义(t=8.510、13.787、10.796,P<0.05);研究组患者肾上腺素(110.35±7.96)pmol/L、C反应蛋白(52.35±6.77)ng/L以及去甲肾上腺素(148.36±6.56)pmol/L水平均低于对照组,差异有统计学意义(t=59.909、40.096、21.155,P<0.05);研究组患者气管拔管时间(24.32±2.32)min、完全清醒时间(45.42±2.48)min、滞留时间(51.43±3.21)min均较对照组显著缩短,差异有统计学意义(t=26.078、56.654、54.409,P<0.05);研究组患者不良反应发生率5.56%较对照组14.44%显著减少,差异有统计学意义(χ^(2)=3.951,P<0.05);研究组术后1、3 dMMSE评分(25.42±0.74)分、(25.78±0.92)分均显著高于对照组,差异有统计学意义(t=23.507、12.548,P<0.05)。结论 在全身麻醉中联合使用舒芬太尼与瑞芬太尼具有显著的麻醉效果,能稳定生命体征指标,降低不良反应发生率,建议推广应用。
Objective To investigate the anesthesia value of sufentanil combined with remifentanil in patients with general anesthesia.Methods A total of 180 patients who underwent general anesthesia surgery in Shanxian Central Hospital from June 2020 to December 2021 were selected. They were equally divided into two groups by random number table method, with 90 patients in each group. The control group was given remifentanil for anesthesia, and the study group was combined with sufentanil and remifentanil for anesthesia. The anesthesia and prognosis of the two groups were compared.Results The fluctuation range of systolic blood pressure(132.12±12.33) mmHg, diastolic blood pressure(78.14±8.61) mmHg, heart rate(74.34±7.49) times/min in the study group was smaller than that in the control group, the difference was statistically significant(t=8.510, 13.787, 10.796, P<0.05). The levels of epinephrine(110.35±7.96) pmol/L, C-reactive protein(52.35±6.77) ng/L and norepinephrine(148.36±6.56) pmol/L in the study group were lower than those in the control group, the difference was statistically significant(t=59.909, 40.096, 21.155,P<0.05). Compared with the control group, the tracheal extubation time(24.32±2.32) min, the fully awake time(45.42±2.48) min and the retention time(51.43±3.21) min in the study group were significantly shortened, the difference was statistically significant(t=26.078, 56.654, 54.409, P<0.05). The incidence of adverse reactions in the study group was 5.56%, which was significantly lower than that in the control group, which was 14.44%, and the difference was statistically significant(χ^(2)=3.951, P<0.05). The MMSE scores(25.42±0.74) points and(25.78±0.92) points in the study group at 1 and 3 days after operation were significantly higher than those in the control group, and the difference was statistically significant(t=23.507, 12.548, P<0.05).Conclusion The combined use of sufentanil and remifentanil in general anesthesia has a significant anesthetic effect, stabilizes vital signs, and reduces the
作者
秦美英
QIN Meiying(Department of Anesthesiology,Shanxian Central Hospital,Heze,Shandong Province,274300 China)
出处
《系统医学》
2022年第16期77-80,共4页
Systems Medicine
关键词
全身麻醉
舒芬太尼
瑞芬太尼
生命体征
麻醉苏醒
不良反应
General anesthesia
Sufentanil
Remifentanil
Vital signs
Anaesthesia resuscitation
Adverse reactions
