摘要
目的 分析卡前列甲酯栓结合新生儿早期基本保健(early essential newborn care, EENC)技术在产后出血(postpartum hemorrhage, PPH)防治中的应用效果及PPH发生的危险因素。方法 选择2018年2月至2020年4月收治于邢台市第三医院足月妊娠分娩的产妇2 123例作为研究对象,按入院时间编号,根据随机数字表法分为A组(1 062例)和B组(1 061例)。两组产妇均接受全程密切监护,进行子宫按摩预防出血。A组给予卡前列甲酯栓,B组在A组基础上采用EENC技术。比较两组母婴健康指标、PPH发生率,采用Logistics多因素回归分析PPH发生的危险因素。结果 A组产妇宫缩持续时间(2.28±0.27)h、恶露持续时间(15.80±3.11)d均长于B组[(2.04±0.31)h、(11.51±2.32)d],PPH发生率(4.05%)高于B组(2.26%),差异有统计学意义(P<0.05)。B组产后2 h、24 h出血量[(101.54±8.32)mL、(317.54±20.82)mL]均少于A组[(121.31±11.31)mL、(381.21±24.31)mL],B组治疗PPH有效率(91.67%)高于A组(67.44%),差异有统计学意义(P<0.05)。多因素分析结果表明子宫肌瘤、前置胎盘和纤维蛋白原降低是引发PPH的独立危险因素。结论 卡前列甲酯栓结合EENC技术可有效预防PPH,具有较好的应用前景。引发PPH的独立危险因素包括子宫瘢痕、前置胎盘和纤维蛋白原水平降低,应引起医师重点关注。
Objective To analyze the application effect of carboprost methylate suppositories combined with early essential newborn care(EENC) in the prevention and treatment of postpartum hemorrhage(PPH) and the risk factors of PPH.Methods A total of 2 123 puerperae who were admitted to Xingtai Third Hospital for full-term pregnancy and childbirth from February 2018 to April 2020 were selected as the research subjects, numbered according to the time of admission, and divided into group A(1 062 cases) and group B(1 061 cases) according to the random number table method.The two groups of women received close monitoring throughout the whole process, and uterine massage was performed to prevent bleeding.Group A was given carboprost methyl ate suppository, and group B was given EENC technology on the basis of group A.The maternal and infant health indicators and the incidence of PPH were compared between the two groups, and logistic regression was used to analyze the risk factors for the occurrence of PPH.Results The duration of uterine contractions(2.28±0.27)h and the duration of lochia(15.80±3.11)d in group A were longer than those in group B [(2.04±0.31)h,(11.51±2.32)d],and the incidence of PPH(4.05%) was higher than that of group B(2.26%),and the difference was statistically significant(P<0.05).The postpartum hemorrhage 2 h, 24 h volume in group B [(101.54±8.32)mL,(317.54±20.82)mL] was less than that in group A [(121.31±11.31)mL,(381.21±24.31)mL],and the difference was statistically significant(P<0.05).The effective rate of treatment of PPH in group B(91.67%) was higher than that in group A(67.44%),and the difference was statistically significant(P<0.05).Multivariate analysis showed that uterine fibroids, placenta previa and decreased fibrinogen were independent risk factors for PPH.Conclusion Carboprost methylate suppositories combined with EENC technique can effectively prevent PPH of puerperae, and has a good application prospect.Independent risk factors for PPH include uterine scarring, placenta previa, and decre
作者
王雪莹
李娟
郑莉霞
刘慧丽
Wang Xueying;Li Juan;Zheng Lixia;Liu Huili(Department of Obsetrics,Xingtai Third Hospital,Xingtai Hebei 054000,P.R.China)
出处
《中国计划生育和妇产科》
2022年第8期94-98,共5页
Chinese Journal of Family Planning & Gynecotokology
基金
邢台市科技计划项目(项目编号:2019ZC216)。
