摘要
目的:研究卡前列甲酯联合葡萄糖酸钙对剖宫产产妇的影响。方法:选取2022年1月—2023年11月三明市第一医院收治的283例剖宫产产妇。根据随机数表法将其分为对照组(140例)和研究组(143例)。对照组给予卡前列甲酯,研究组在对照组基础上给予葡萄糖酸钙。比较两组产后出血量,用药前、用药后1 h血压、血清指标、凝血功能及不良反应。结果:研究组产后2 h、12 h、24 h出血量少于对照组,差异有统计学意义(P<0.05)。用药前后,两组舒张压与收缩压比较,差异无统计学意义(P>0.05)。用药后1 h,研究组血清钙水平均高于对照组,差异有统计学意义(P<0.05)。用药后1 h,研究组凝血酶原时间、活化部分凝血活酶时间均短于对照组,纤维蛋白原均高于对照组,差异有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:卡前列甲酯联合葡萄糖酸钙在剖宫产产后出血防治中可以减少产后出血量,提高血清钙水平及凝血功能。
Objective:To study the effect of Carboprost Methyl Ester combined with Calcium Gluconate on parturient in cesarean section.Method:A total of 283 cases of cesarean section delivered in Sanming First Hospital from January 2022 to November 2023 were selected.They were divided into control group(140 cases)and study group(143 cases)according to random number table method.The control group was given Carboprost Methyl Ester,and the study group was given Calcium Gluconate on the basis of the control group.Postpartum blood loss volume,blood pressure,serum indexes,coagulation function before and 1 h after medication and adverse reactions were compared between the two groups.Result:The postpartum blood loss volume of 2 h,12 h and 24 h in the study group was less than that in the control group,and the difference was statistically significant(P<0.05).Before and after medication,there was no significant difference in diastolic and systolic blood pressure between the two groups(P>0.05).After 1 h of medication,the serum calcium level of the study group was higher than that of the control group,and the difference was statistically significant(P<0.05).After 1 h of medication,the prothrombin time and activated partial thromboplastin time in the study group were shorter than those in the control group,and the fibrinogen were higher than those in the control group,the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Carboprost Methyl Ester combined with Calcium Gluconate can reduce postpartum hemorrhage and improve serum calcium level and coagulation function in the prevention and treatment of postpartum hemorrhage.
作者
赵勇
黄焱
ZHAO Yong;HUANG Yan(Sanming First Hospital,Sanming 365001,China;不详)
出处
《中外医学研究》
2024年第28期114-117,共4页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
剖宫产
产后出血
卡前列甲酯
葡萄糖酸钙
Cesarean section
Postpartum hemorrhage
Carboprost Methyl Ester
Calcium Gluconate
