摘要
目的 探讨弥散加权成像在脑梗塞合并抑郁症患者中的诊断效果及与功能障碍的关系。方法 选择2017年4月至2019年12月脑梗塞患者93例作为对象,均经血管造影检查确诊“金标准”,并完成汉密尔顿抑郁量表(HAMD)评估;根据结果 分为脑梗塞组和合并组。确诊前所有患者均完成弥散加权成像检查,并将检查结果 与“金标准”进行比较;绘制ROC曲线,分析弥散加权成像在脑梗死合并抑郁症患者中的诊断效能;采用蒙特利尔认知评估量表(MoCA)对患者认知功能进行评估;采用改良Rankin量表、肌力Lovett法对患者日常生活能力、肢体功能进行评估;采用SPSS Pearson相关性分析软件对患者诊断效果与功能障碍进行相关性分析。结果 93例脑梗塞患者均经造影检查确诊,DWI最终确诊90例,与金标准诊断符合率为96.77%(P>0.05);ROC曲线结果 表明:弥散加权成像用于脑梗塞合并抑郁症患者中AUC值为0.851,诊断灵敏度为0.863%,诊断特异度为0.615%;93例脑梗塞患者均完成抑郁症筛查,其中34例确诊为抑郁症,发生率为3 6.5 5%。合并组患者改良Rankin量表评分高于单一组(P<0.05);MoCA评分、肌力Lovett法评分低于单一组(P<0.05);SPSS Pearson相关性分析结果 表明:弥散加权成像在脑梗塞合并抑郁症患者中的检出率与MoCA及肌力Lovett法评分呈负相关性(P<0.005);与改良Ran kin量表评分呈正相关性(P<0.05)。结论 弥散加权成像用于脑梗塞合并抑郁症患者中能获得较高的检出率及诊断效能,且与功能障碍存在相关性。
Objective To investigate the diagnostic efficacy of diffusion-weighted imaging in patients with cerebral infarction complicated with depression and its relationship with functional impairment.Methods 93 patients with cerebral infarction from April 2017 to December 2019 were selected as subjects.All of them were confirmed by angiography "gold standard" and completed the evaluation of Hamilton Depression Scale(HAMD).According to the results,the patients were divided into cerebral infa rction group and combined group.Before diagnosis,all patients completed diffuse-weighted imaging examination,and the examination results were compared with the "gold standard".ROC curve was drawn to analyze the diagnostic efficacy of diffusion-weighted imaging in patients with cerebral infarction complicated with depression.The patients’ cognitive function was evaluated with The Montellier Cognitive Assessment Scale(MoCA).The improved Rankin scale and Lovett method were used to evaluate the daily life ability and limb function of the patients.SPSS and Pearson correlation analysis software was used to analyze the correlation between the diagnosis effect and dysfunction of patients.Results all the 93 patients with cerebral infarction were confirmed by angiography,and90 cases were finally confirmed by DWI,which was consistent with the gold standard diagnosis rate of 96.77%(P>0.05).The RESU LTS of ROC cu rve showed that the AUC value,diagnostic sensitivity and diagnostic specificity of diffusion-weighted imaging for patients with ce rebral infa rction and depression were 0.851,0.863% and 0.615% respectively.All the 93 patients with cerebral infarction completed depression screening,34 of whom were diagnosed with depression,with an incidence of 36.55%.The score of modified Rankin scale in the combined group was higher than that in the single group(P<0.05).MoCA score and Lovett score were lower than those of single group(P<0.05).The results of SPSS Pearson correlation analysis showed that the detection rate of diffuse-weighted imaging in
作者
黄汉军
鲁凤荣
张灿
Huang Han-jun;Lu Feng-rong;Zhang Can(Department of Medical Imaging,Wuhan Mental Health Center,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430012,Hubei Province,China;Department of Radiology,Union Medical College Affiliated to Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,Hubei Province,China)
出处
《中国CT和MRI杂志》
2022年第9期9-10,24,共3页
Chinese Journal of CT and MRI
关键词
弥散加权成像
脑梗塞
抑郁症
诊断效果
功能障碍
ROC曲线
相关性分析
Diffusion Weighted Imaging
Cerebral Infarction
Depression
Diagnostic Results
Dysfunction
ROC Curve
Correlation Analysis