摘要
现代通信技术的快速发展与广泛应用,使得人们日常生活中使用电子设备越来越多,进而引发对电磁辐射是否损害健康更加密切的关注。一方面,已有许多研究表明,电磁辐射暴露影响人类或其他生物的健康,如电磁辐射暴露已被发现与多种疾病的高发生率相关,射频电磁场也被列为2B类致癌物;另一方面,电磁辐射可以作为一些疾病的治疗手段,如癌症的放射治疗、热磁疗等。文章通过整理多组学分析的研究成果,从细胞生物信息学、基因组学、转录组学、蛋白质组学、代谢组学、微生物组学等六个方面分别总结了电磁辐射对不同组学的影响及其生物学机制。这些研究结果可以帮助人们更好地认识电磁辐射,并对日常生活中电磁辐射可能造成的危害进行预防。
Due to the rapid development of modern communications technology,people are utilizing portable electronic devices more frequently in their daily lives,which has led to concerns about whether electromagnetic radiation(EMF)can be harmful to health. Many studies have demonstrated that exposure to EMF can influence an organism’s or a person’s health. For instance,EMF exposure has been identified as a Group 2B carcinogen and has been associated with a high incidence of numerous disorders. On the other hand,EMF exposure can also be used as a treatment for some diseases,such as radiation therapy and thermomagnetic therapy for cancer. By compiling research findings based on multi-omics big data analysis,this review summarizes the effects of EMF on human health in various omics environments and their biological mechanisms from six aspects respectively: cellular bioinformatics,genomics,transcriptomics,proteomics,metabolomics,and microbiomics. These discoveries can assist individuals to reduce the risks of EMF in their daily lives and have better understanding of the impacts of EMF on human health.
作者
曹晨
沈艳
顾宁
CAO Chen;SHEN Yan;GU Ning(School of Biomedical Engineering and Informatics,Nanjing Medical University,Nanjing 211166;School of Medicine,Nanjing University,Nanjing 210002;Jiangsu Key Laboratory for Biomaterials and Devices,Nanjing 210009,China)
出处
《南京医科大学学报（社会科学版）》
2022年第4期318-324,共7页
Journal of Nanjing Medical University（Social Sciences）
基金
国家自然科学基金创新研究群体项目(61821002)
国家自然科学基金青年基金项目(62102068)。
关键词
电磁辐射
健康
多组学
electromagnetic radiation
health
multi-omics
