期刊文献+

依托咪酯药理作用、药物代谢动力学及毒理学研究 被引量:14

原文传递
导出
摘要 依托咪酯是一种咪唑类短效静脉用麻醉药,适用于短期手术过程中的麻醉诱导,目前它已有三十多年的使用历史。由于依托咪酯不属于管制类精神药品或者麻醉药品,当前已存在一定滥用风险。本文就近些年来依托咪酯分子的药理学特征、药物代谢动力学、毒性反应和新型依托咪酯衍生物的相关研究进行详细阐述,有助于对依托咪酯的作用机理的认识和毒害性评估。
出处 《广东公安科技》 2022年第2期43-45,共3页
  • 相关文献

参考文献3

二级参考文献45

  • 1Bovill JG.Intravenous anesthesia for the patient with left ventricular dysfunction[J].Semin Cardiothorac Vasc Anesth,2006,10:43-48. 被引量:1
  • 2Johnson KB,Egan TD,Layman J.The influence of hemorrhagic shock on etomidate:A pharmacokinetic and pharmacodynamic analysis[J].Anesth Analg,2003,96:1360-1368. 被引量:1
  • 3Zuckerbraun NS,Pitetti RD,Herr SM,et al.Use of etomidate as an induction agent for rapid sequence intubation in a pediatric emergency department[J].Acad Emerg Med,2006,13:602-609. 被引量:1
  • 4Kaneda K,Yamashita S,Woo S,et al.Population pharmacokinetics pharmacodynamics of brief etomidate infusion in healthy volunteers[J].J Clin Pharmacol,2011,51(4):482-491. 被引量:1
  • 5Nyman Y,Von Hofsten K,Palm C,et al.Etomidate-lipuro is associated with considerably less injection pain in children compared with propofol with added lidocaine[J].Br J Anaesth,2006,97:536-539. 被引量:1
  • 6Hwang JY,Kim JH,Oh AY,et al.A comparison of midazolam with remifentanil for the prevention of myoclonic movements following etomidate injection[J].J Int Med Res,2008,36:17-22. 被引量:1
  • 7Mizrak A,Koruk S,Bilgi M,et al.Pretreatment with dexmedetomidine or thiopental decreases myoclonus after etomidate:A randomized,double-blind controlled trial[J].J Surg Res,2010,159:e11-16. 被引量:1
  • 8Annane D,Sebille V.Corticosteroids for patients with septic shock[J].JAMA,2003,289:43-44. 被引量:1
  • 9Sprung CL,Annane D,Keh D,et al.CORTICUS study group:hydrocortisone therapy for patients with septic shock[J].N Engl J Med,2008,358:111-124. 被引量:1
  • 10Cuthbertson BH,Sprung CL,Annane D,et al.The effects of etomidate on adrenal responsiveness and mortality in patients with septic shock[J].Intensive Care Med,2009,35:1868-1876. 被引量:1

共引文献15

同被引文献80

引证文献14

二级引证文献14

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部