摘要
目的 探讨门冬氨酸钾镁联合美托洛尔治疗心律失常的有效性与安全性。方法 选择2019年1月至2020年12月我院收治的98例心律失常患者为研究对象,依据入院编号的奇偶性将其分为对照组(美托洛尔治疗)与试验组(在对照组基础上联合门冬氨酸钾镁治疗),各49例。比较两组的治疗效果。结果 试验组的治疗总有效率高于对照组(P<0.05)。两组的不良反应总发生率比较,差异无统计学意义(P>0.05)。治疗后,试验组的左心室舒张末期内径(LVEDD)、左心室后壁舒张末期厚度(LVPWT)、室间隔舒张末期厚度(IVSD)、左心室射血分数(LVEF)优于对照组(P<0.05)。治疗后,试验组的全血低切黏度(LBV)、全血高切黏度(HBV)、血细胞比容(HCT)、红细胞沉降率(ESR)低于对照组(P<0.05)。结论 门冬氨酸钾镁联合美托洛尔治疗心律失常的效果显著,有利于提升患者的心功能,改善血液流变学指标,同时不会增加用药风险,安全性高。
Objective To investigate the efficacy and safety of potassium magnesium aspartate combined with metoprolol in the treatment of arrhythmia.Methods Ninety-eight patients with arrhythmia admitted in our hospital from January 2019 to December 2020 were selected as the research objects,the patients were divided into control group(metoprolol treatment)and experimental group(potassium magnesium aspartate treatment on the basis of the control group)according to the parity of admission number,with 49 cases in each group.The therapeutic effects of the two groups were compared.Results The total effective rate of treatment of the experimental group was higher than that of the control group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).After treatment,the left ventricular end diastolic diameter(LVEDD),left ventricular posterior wall end-diastolic thickness(LVPWT),interventricular septum end diastolic thickness(IVSD)and left ventricular ejection fraction(LVEF)in the experimental group were better than those in the control group(P<0.05).After treatment,the low blood viscosity(LBV),high blood viscosity(HBV),hematocrit(HCT)and erythrocyte sedimentation rate(ESR)in the experimental group were lower than those in the control group(P<0.05).Conclusion Potassium magnesium aspartate combined with metoprolol in the treatment of arrhythmia has remarkable effect,which is conducive to improving the heart function of patients and the hemorheology indexes,without increasing the risk of medication,and has high safety.
作者
赵卫民
孙屹屹
ZHAO Weimin;SUN Yiyi(Critical Care Medicine Department,the People's Hospital of Qi Xian,Hebi 456750;Critical Care Medicine Department,the People's Hospital of Hebi,Hebi 458030,China)
出处
《临床医学研究与实践》
2022年第25期69-71,共3页
Clinical Research and Practice
关键词
心律失常
门冬氨酸钾镁
美托洛尔
arrhythmia
potassium magnesium aspartate
metoprolol
