摘要
目的介绍河南省围产儿出生缺陷(birth defects,BDs)情况,分析围产儿先天性心脏病的流行病学特征。方法通过河南省妇幼监测系统和分娩机构的出生医学证明,收集2018—2019年河南省先天性心脏病患儿信息和活产儿总数,选取2018—2019年出生的先天性心脏病患儿及同期分娩有先天性心脏病患儿的孕产妇为研究对象,统计分析河南省先天性心脏病的发病率和病因顺位,以及不同性别、城乡、母亲年龄的先天性心脏病患儿的构成比。结果本研究涉及2018—2019年河南省活产儿2409990例,其中BDs患儿23572例,包括75所监测医院14068例,461所非监测医院9504例。2018—2019年河南省BDs发病率由2018年的91.78/万上升至2019年的104.14/万,年增长率为13.47%,总发病率为97.81/万。先天性心脏病高居BDs发病率中第1位,且2019年发病率高于2018年。在先天性心脏病发病亚型中,排名前3位的分别为房间隔缺损/卵圆孔未闭、动脉导管未闭及室间隔缺损,构成比分别为58.82%、34.61%和9.95%。结论应加强孕产妇孕期宣教和产前筛查诊断工作,及时发现围产儿潜在先天性缺陷,降低出生缺陷率;进一步完善出生缺陷监测方案,加强监测力度,减少漏报情况的发生。
Objective To describe the situation of perinatal birth defects(BDs)in Henan Province and analyze the epidemiological characteristics of perinatal congenital heart disease(CHD).Methods The information of children with CHD and the total number of live births in Henan Province from 2018 to 2019 were collected through Henan Provincial Maternity and Child Monitoring System and birth medical certificate of delivery institution.Study subjects were the children with CHD born from 2018 to 2019 and pregnant women who delivered children with CHD during the same period.Incidence of CHD and the rank of disease causes,as well as the proportion ratios of CHD of different genders,urban or rural areas,and maternal ages were analyzed.Results There were 2409990 live births in Henan Province from 2018 to 2019,among which 23572 children were BDs,including 14068 from 75 surveillance hospitals and 9504 from 461 non-surveillance hospitals.The incidence of BDs in Henan Province increased from 91.78/10000 in 2018 to 104.14/10000 in 2019,with an annual growth rate of 13.47%and an overall incidence rate of 97.81/10000.The incidence of CHD ranked the first in BDs,and its incidence was higher in 2019 than that in 2018.Among the sub-types of CHD,the top three were atrial septal defect/patent foramen ovale,patent duct us arteries us and ventricular septal defect,with proportion ratios of 58.82%,34.61%and 9.95%,respectively.Conclusion Maternal health education during pregnancy and prenatal screening/diagnosis should be strengthened to timely detect potential congenital defects and decrease the rate of birth defects.At the same time,birth defect surveillance program should be further improved to strengthen monitoring and reduce the occurrence of under-reporting.
作者
于硕
王蕊
陈露
任琛琛
赵悦淑
YU Shuo;WANG Rui;CHEN Lu;REN Chen Chen;ZHAO Yue Shu(The Third Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,Henan Province,China)
出处
《中国妇幼卫生杂志》
2022年第2期48-51,共4页
Chinese Journal of Women and Children Health
关键词
先天性心脏病
出生缺陷
流行病学
围产儿
congenital heart disease
birth defects
epidemiology
perinatal infant
