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2016—2020年河南省多中心妊娠合并症/并发症及母婴结局相关因素分析 被引量:9

Factors associated with pregnancy complication/comorbidity and maternal-infant outcomes in Henan in 2016—2020: a multicenter observation
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摘要 目的 了解2016—2020年河南省妊娠合并症/并发症的发生情况,探讨河南省妊娠合并症/并发症的高危因素及母婴结局,为预防妊娠合并症/并发症的发生及改善母婴结局提供理论支持。方法 回顾性分析2016年1月1日—2020年12月31日河南省32家危重孕产妇监测医院住院分娩的孕妇资料,分析妊娠合并症/并发症发生的高危因素及母婴结局,采用二元logistic回归分析妊娠合并症/并发症的发生风险。结果 2016—2020年河南省32家危重孕产妇医院共监测住院分娩孕产妇631 463例,共253 599例孕妇发生妊娠合并症/并发症。2016—2020年妊娠合并症/并发症的发病率呈现逐年增长的趋势。在年龄≥35岁、市级及以上医院分娩、妊娠次数=1次、产次=0次、既往剖宫产次数≥1次、产前检查次数≥5次、本次妊娠胎儿数≥2、婚姻状况为单身/离异/丧偶/其他、孕妇教育程度在大专及大专以上的人群中,妊娠合并症/并发症检出率较高(P<0.01)。二元logistic回归分析显示,年龄≥35岁、妊娠次数≥2次、既往剖宫产次数≥1次、产前检查≥5次、本次妊娠胎儿数≥2是妊娠合并症/并发症发生的危险因素,结果均具有统计学意义(P<0.01)。妊娠合并症/并发症组中剖宫产、新生儿体质量中巨大儿及低出生体质量儿、死产发生率也高于对照组(P<0.01)。结论 妊娠合并症/并发症发生率逐渐上升,且增加不良母婴结局的发生风险,应做到孕前保健、孕期宣教,定期接受孕期检查,及时发现危险因素并有效纠正。对已发生妊娠期合并症/并发症进行针对性健康教育、全面合理诊疗和有效规范管理,降低不良妊娠结局,保障母婴安全,提高产科出生人口质量。 Objective To explore the high-risk factors associated with pregnancy complication/comorbidity and maternal-infant outcomes in Henan province, and to provide theoretical support for preventing pregnancy complication/comorbidity and improving maternal-infant outcomes. Methods A retrospective analysis was performed on data of pregnant women who gave birth in 32 critically ill maternal monitoring hospitals in Henan province from January 1, 2016 to December 31, 2020.The high-risk factors associated with pregnancy complication/comorbidity and pregnancy outcomes were analyzed, and binary logistic regression model was used to analyze the risks of pregnancy complications. Results A total of 631 463 maternal hospital deliveries were monitored in 32 critical maternity hospitals in Henan province from 2016 to 2020, and 253 599 pregnant women had pregnancy complication/comorbidity.The incidence of pregnancy complication/comorbidity showed an up-ward trend from 2016 to 2020.The incidences of pregnancy complication/comorbidity were higher among women with maternal age of ≥35 years,who give birth in municipal hospitals or higher level hospitals,the first time pregnancy and no history of delivery,with one or more cesarean deliveries,5 times or more matenatal checkups,with multiple fetuses in the current pregnany,who were single/divorced/widowed/other,and with college or higher education(P<0.01).Binary logistic regression analysis showed that age ≥35 years old,pregnancies of ≥2 times,cesarean deliveries of ≥1,maternal visits ≥5 times,and number of fetuses≥ 2in the current pregnancy were risk factors for pregnancy complication/comorbidity,and the results were statistically significant(P< 0.01).Women with pregnancy complication/comorbidity were more likely to have cesarean delivery,give birth to overweight or low weight babies or have stillbirths compared to women in the control group(P<0.01). Conclusions The incidence of pregnancy complication/comorbidity goes up gradually,which increases the risk of adverse maternal an
作者 徐冬梅 李心童 张丽 曹瑞敏 张红艳 郝倚德 XU Dong-mei;LI Xin-tong;ZHANG Li;CAO Rui-min;ZHANG Hong-yan;HAO Yi-de(Ministry of maternity care,Third Affiliated Hospital of Zhengzhou University,Zhengzhou,Henan 450052,China;不详)
出处 《中国预防医学杂志》 CAS CSCD 北大核心 2022年第6期462-468,共7页 Chinese Preventive Medicine
基金 河南省2020高等学校重点科研项目(20A320041)。
关键词 妊娠合并症/并发症 母婴结局 影响因素 Pregnancy complication/comorbidity Maternal and infant outcomes Influencing factor
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