摘要
目的:观察接骨七厘片联合交锁髓内钉固定术治疗胫腓骨骨折的临床疗效。方法:将120例胫腓骨骨折患者随机分为研究组62例与对照组58例。对照组给予交锁髓内钉固定术,研究组采用交锁髓内钉固定术联合接骨七厘片治疗。于术后12周比较2组血小板衍生生长因子(PDGF)、骨形态发生蛋白-2 (BMP-2)、血管内皮生长因子(VEGF)水平、AOFAS踝-后足评分量表(AOFAS)评分及术后并发症发生率。结果:术前,2组PDGF、BMP-2、VEGF水平比较,差异无统计学意义(P>0.05);术后12周,2组上述骨愈合指标水平均较治疗前升高(P<0.05),且研究组各项指标均高于对照组(P<0.05)。术前,2组AOFAS量表中疼痛感、活动与步行、稳定性与形状等维度评分比较,差异无统计学意义(P>0.05);术后12周,2组上述各维度评分均较治疗前升高,且研究组各维度评分均高于对照组(P<0.05)。研究组术后并发症发生率为6.45%,对照组为17.24%,2组比较,差异有统计学意义(P<0.05)。结论:交锁髓内钉固定术联合接骨七厘片可促进胫腓骨骨折患者骨痂生长,有效改善小腿功能,且并发症发生率相对较低,安全性好。
Objective:To observe the clinical effect of the therapy of Jiegu Qili tablets combined with interlocking intramedullary nail fixationon patients with tibiofibula fracture. Methods:A total of 120 cases with tibiofibula fracture of qi stagnation and blood stasis type were randomly divided into the study group(62 cases) and the control group(58 cases). The control group was treated with interlocking intramedullary nail fixation, and the study group was treated with interlocking intramedullary nail fixation combined with Jiegu Qili tablets. The levels of platelet-derived growth factor(PDGF),bone morphogenetic protein-2(BMP-2) and vascular endothelial growth factor(VEGF) were compared between the two groups twelve weeks after surgery,and the scores of American Orthopedic Foot and Ankle Society(AOFAS) and the incidence of postoperative complications were compared between the two groups. Results: Before surgery, there was no significant difference in the comparison of levels of PDGF, BMP-2 and VEGF between the two groups(P>0.05);twelve weeks after surgery, the levels of the above bone healing indexes in both groups were higher than those before treatment(P<0.05),and all levels in the study group were higher than those in the control group(P<0.05). Before surgery,there was no significant difference in the comparisons of scores of pain sensation,activity and walking,stability and shape in AOFAS between the two groups(P>0.05);twelve weeks after surgery,the scores of the above dimensions in both groups were increased when compared with those before treatment, and the above scores in the study group were higher than those in the control group(P<0.05). After surgery,the total complication rate was 6.45%in the study group and 17.24% in the control group,the difference being significant(P<0.05). Conclusion:The therapy of Jiegu Qili tablets combined with interlocking intramedullary nail fixation can promote callus growth and improve calf function in patients with tibiofibular fracture,and the incidence of complications is relati
作者
李彬
李广彬
LI Bin;LI Guangbin
出处
《新中医》
CAS
2022年第14期95-98,共4页
New Chinese Medicine
关键词
胫腓骨骨折
交锁髓内钉固定术
接骨七厘片
骨形态发生蛋白-2
Tibiofibula fracture
Interlocking intramedullary nail fixation
Jiegu Qili tablets
Bone morphogenetic protein-2
